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品种反应性 主要应用 宿主 格式 抗体类型 Ca, H, M, Rhesus Macaque, B, Po ICC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN41 描述 Anti-FGF9 Antibody Alternate Names - HBGF-9
- Glia-activating factor
- GAF
- Fibroblast growth factor 9
- FGF-9
- Heparin-binding growth factor 9
背景信息 Fibroblast growth factors are a family of intercellular signaling molecules that serve various roles in a number of different species. Most Fibroblast growth factors are exported from cells via a classical amino-terminal signal sequence that is cleaved from the mature protein during its passage through the secretory pathway. Like its other family members, Fibroblast growth factor-9 (FGF-9) is secreted from cells; however, it is different in that it does not contain a recognizable signal sequence. Also known as Glia-activating factor (GAF), FGF-9 is glycosylated, mildly hydrophobic, and secreted from glioma cells. It is suggested to play a critical role in myoblast migration, glial cell growth, glial differentiation, gliosis during repair and regeneration of brain tissue after damage, and in the survival of neuronal cells and glial tumors. Abnormal functioning of this molecule is associated with skeletal dysplasias, and autosomal dominant craniosynostosis syndromes. 产品信息 格式 Affinity Purified 控制 - Human cerebellum tissue lysate.
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-FGF9 Antibody is an antibody against FGF9 for use in IH(P) & IC. 主要应用 - Immunocytochemistry
应用说明 Immunocytochemistry Analysis: 2 µg/mL of this antibody detected FGF9 in NIH/3T3 cells. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human FGF9. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 CanineHumanMouseRhesus MacaqueBovinePig Species Reactivity Note Demonstrated to react with Human and Mouse. Predicted to react with Rhesus Macaque, Bovine, Porcine, and Canine based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_002001
Entrez基因汇总 The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. 基因符号 - FGF9
纯化方法 Affinity purified UniProt编号 - P31371
UniProt汇总 FUNCTION: May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
SUBUNIT STRUCTURE: Monomer.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Glial cells.产品使用声明 质量保证 Evaluated by Immunohistochemistry in human cerebellum tissue.
Immunohistochemistry Analysis: A 1:200 dilution of this antibody detected FGF9 in human cerebellum tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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