merck millipore,默克密理博,ABF235,Anti-TICAM2 Antibody

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merck millipore,默克密理博,ABF235,Anti-TICAM2 Antibody
产品名称：Anti-TICAM2 Antibody
产品型号：ABF235
Anti-TICAM2 Antibody is a highly specific rabbit polyclonal antibody, that targets TIR domain-containing adapter molecule 2 & has been tested in western blotting.

merck millipore,默克密理博,ABF235,Anti-TICAM2 Antibody

产品介绍

merck millipore,默克密理博,ABF235,Anti-TICAM2 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABF235
描述	Anti-TICAM2 Antibody
Alternate Names	TICAM2 TIR domain-containing adapter molecule 2 TICAM-2 Putative NF-kappa-B-activating protein 502 TRIF-related adapter molecule Toll-like receptor adaptor protein 3 Toll/interleukin-1 receptor domain-containing protein MyD88-4
背景信息	TIR domain-containing adapter molecule 2 (TICAM2), also known as Toll/interleukin-1 receptor domain-containing protein (TIRP), also known as Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule (TRAM), and Toll-like receptor adaptor protein 3 (TIRAP3), is an adaptor protein containing one TIR domain, and is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) serving as an important link between the innate and adaptive immune responses. TICAM2 has been shown to play an important role as a sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. TICAM2 interacts with TLR4 and TICAM1, and functionally transmits LPS-TRL4 signal to TICAM1. Recent studies suggest that TICAM2 may also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. TICAM2 is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Anti-TICAM2 Antibody is a highly specific rabbit polyclonal antibody, that targets TIR domain-containing adapter molecule 2 & has been tested in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human TICAM2.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Human
抗体类型	Polyclonal Antibody
基因符号	TRAM TICAM2 TIRAP3 TIRP
纯化方法	Antigen Affinity purified
UniProt编号	Q86XR7

产品使用声明
质量保证	Evaluated by Western Blotting in PC3 cell lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected TICAM2 in PC3 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.