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品种反应性 主要应用 宿主 格式 抗体类型 H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABF13 描述 Anti-Interleukin-10 Antibody Alternate Names - CSIF
- Interleukin-10
- IL-10
- Cytokine synthesis inhibitory factor
背景信息 Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. IL-10 down regulates the expression of Th1 cytokines, major histocompatibility complex class II antigens, and costimulatory molecules on macrophages. It also enhaces B cell survival, proliferation, and antibody production. Knockout studies suggest that IL-10 is an immunoregulator in the intestinal tract. 产品信息 格式 Affinity Purified 控制 - Mouse Interleukin-10 recombinant protein
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Interleukin-10 using this Anti-Interleukin-10 Antibody validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to mouse Interleukin-10. 宿主 Rabbit 品种反应性 HumanMouse Species Reactivity Note Demonstrated to react with Mouse and Human. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_034678
基因符号 - Il-10
- Il10
纯化方法 Affinity purified UniProt编号 - P18893
UniProt汇总 FUNCTION: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
SUBUNIT STRUCTURE: Homodimer (By similarity).
SUBCELLULAR LOCATION: Secreted.
SEQUENCE SIMILARITIES: Belongs to the IL-10 family.产品使用声明 质量保证 Evaluated by Western Blot in mouse Interleukin-10 recombinant protein.
Western Blot Analysis: 0.01 µg/mL of this antibody detected Interleukin-10 on 10 µg of mouse Interleukin-10 recombinant protein.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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