- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,MABT395,Anti-Muc4 Antibody, clone 8G7
产品名称：Anti-Muc4 Antibody, clone 8G7
产品型号：MABT395
Anti-Muc4 Antibody, clone 8G7 is a highly specific mouse monoclonal antibody, that targets Mucin & has been tested in western blotting & IHC.
merck millipore,默克密理博,MABT395,Anti-Muc4 Antibody, clone 8G7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT395 描述 Anti-Muc4 Antibody, clone 8G7 Alternate Names - Mucin-4 beta chain
背景信息 Mucin-4 (MUC-4 or Muc4) is also called Ascites sialoglycoprotein (ASGP), Pancreatic adenocarcinoma mucin, Testis mucin, and Tracheobronchial mucin. Muc4 is proteolytically cleaved into two chains: mucin-4 alpha chain and mucin-4 beta chain. Muc4 has anti-adhesive properties and is involved in tumor progression, cell proliferation and differentiation of epithelial cells. Muc4 is expressed in the thymus, thyroid, lung, trachea, esophagus, stomach, small intestine, colon, testis, prostate, ovary, uterus, placenta, mammary and salivary glands as well as lung cancers, squamous cell carcinomas of the upper aerodigestive tract, mammary carcinomas, biliary tract, colon, cervix cancers, pancreatic tumors, and pancreatic tumor cell lines. The expression of Muc4 has become a very useful indicator of poor prognosis in patients with invasive ductal carcinoma and intrahepatic cholangiocarcinoma, mass forming type (IDC,ICC-MF), where patients with high Muc4 expression had lower survival rates than those with low Muc4 expression. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl without preservatives. 应用 应用 Anti-Muc4 Antibody, clone 8G7 is a highly specific mouse monoclonal antibody, that targets Mucin & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Muc4 in human ilium tissues.
Western Blotting Analysis: A representative lot from an independent laboratory detected Muc4 in maligant melanoma and cutaneous squamous cell carcinoma tissue lysates (Moniaux, N., et al. (2004). J Histochem Cytochem. 52(2):253-261.).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Muc4 in lung adenocarcinoma and pancreatic adenocarcinoma tissues (Moniaux, N., et al. (2004). J Histochem Cytochem. 52(2):253-261.).
Immunohistochemistry Analysis: A representative lot from independent laboratories detected Muc4 in 330 tissue spots representing normal skin, and benign and malignant cutaneous diseases (Singh, A. P., et al. (2006). Prostate. 66(4):421-429.; Chakraborty, S., et al. (2010). J Clin Pathol. 63(7):579-584.).生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the beta chain tandem repeat region of human Muc4. 克隆 8G7 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - MUC4
纯化方法 Protein G purified UniProt编号 - E7EW47
产品使用声明 质量保证 Evaluated by Western Blotting in CD18/HPAF cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected Muc4 in 10 µg of CD18/HPAF cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,07-590,Anti-Ago 2 Antibody
下一件merck millipore产品：merck millipore,默克密理博,448101,Met Kinase Inhibitor - CAS 658084-23-2 - Calbiochem
相关产品
merck millipore,默克密理博,444264,MMP Inhibitor III - CAS 927827-98-3 - Calbiochem
merck millipore,默克密理博,ABF13,Anti-Interleukin-10 Antibody
merck millipore,默克密理博,AP112F-K,Goat Anti-Human IgG/H&L, Fluorescein (1mg)
merck millipore,默克密理博,07-590,Anti-Ago 2 Antibody
merck millipore,默克密理博,448101,Met Kinase Inhibitor - CAS 658084-23-2 - Calbiochem
merck millipore,默克密理博,0110-3480,Guava PCA-96 IQ/OQ Document
merck millipore,默克密理博,MABN270,Anti-alpha-dystrobrevin Antibody, clone 1D11.1
merck millipore,默克密理博,4500-0550,Guava Caspase 8 FAM Kit for Flow Cytometry
merck millipore,默克密理博,14-197,Casein Kinase 2 Protein, active, 10 µg