- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,07-584,Anti-HMGB1/HMG-1 Antibody
产品名称：Anti-HMGB1/HMG-1 Antibody
产品型号：07-584
Anti-HMGB1/HMG-1 Antibody is a Rabbit Polyclonal Antibody for detection of HMGB1/HMG-1 also known as High-mobility group box 1 & has been validated in WB.
merck millipore,默克密理博,07-584,Anti-HMGB1/HMG-1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-584 品牌系列 Upstate
商名 - Upstate
描述 Anti-HMGB1/HMG-1 Antibody Alternate Names - high-mobility group box 1
- High mobility group protein 1
- Sulfoglucuronyl carbohydrate binding protein
- high mobility group box 1
- high-mobility group (nonhistone chromosomal) protein 1
背景信息 HMG-1 (High-Mobility-Group protein, amphoterin) is a highly conserved protein with more than 95% amino acid identity between rodent and human HMG-1. It is a prevalent non-histone chromatin component and a non-sequence specific DNA binding protein. HMG-1 consists of two homologous HMG boxes rich in basic amino acids and an acidic tail at the carboxy-terminus. HMG-1 is involved in the regulation of chromatin structure as well as being involved, either as positive or negative factors with various aspects of DNA replication, transcription, repair, and ligation. HMG-1, identified as a membrane associated protein termed “amphoterin,” mediates neurite outgrowth, tumor outgrowth, and metastasis. It participates in plasminogen activation and is recognized as a late mediator of endotoxin lethality in mice. 产品信息 格式 Purified 控制 - Acid extracted proteins from HeLa cells.
演示 Purified rabbit polyclonal IgG in buffer containing 70% storage buffer 0.1 M Tris-glycine, pH 7.4, 0.15 M NaCl, 0.05% sodium azide and 30% glycerol. 应用 应用 Anti-HMGB1/HMG-1 Antibody is a Rabbit Polyclonal Antibody for detection of HMGB1/HMG-1 also known as High-mobility group box 1 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 HMGB1/HMG-1 protein purified from pig thymus glands. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes HMGB1/HMG-1, MW ~32 kDa. 同种型 IgG 品种反应性 Human Species Reactivity Note Human. Broad species cross-reactivity is expected. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_002119
基因符号 - SBP-1
- HMGB1
- HMG1
- Amphoterin
- DKFZp686A04236
- HMG3
纯化方法 Protein A purfied UniProt编号 - P09429
UniProt汇总 FUNCTION: SwissProt: P09429 # Binds preferentially single-stranded DNA and unwinds double stranded DNA.
SIZE: 215 amino acids; 24894 Da
SUBCELLULAR LOCATION: Nucleus.
SIMILARITY: SwissProt: P09429 ## Belongs to the HMGB family. & Contains 2 HMG box DNA-binding domains.产品使用声明 质量保证 Evaluated in acid extracted proteins from HeLa cells.
Western Blot Analysis:
1-2 μg/mL of this antibody detected HMGB1/HMG-1 in acid extracted proteins from HeLa cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20ºC from date of receipt. 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,07-609,Anti-Peroxiredoxin 1 Antibody
下一件merck millipore产品：merck millipore,默克密理博,444264,MMP Inhibitor III - CAS 927827-98-3 - Calbiochem
相关产品
merck millipore,默克密理博,04-079,Anti-trimethyl-Histone H4 (Lys20), Antibody, rabbit monoclonal
merck millipore,默克密理博,MAB5326C3,Anti-Nestin Antibody, clone 10C2, Cy3 conjugate
merck millipore,默克密理博,ABD49,Anti-Pw1/Peg3 Antibody
merck millipore,默克密理博,NR07,Anti-Ryanodine Receptor Mouse mAb (C3-33)
merck millipore,默克密理博,07-609,Anti-Peroxiredoxin 1 Antibody
merck millipore,默克密理博,444264,MMP Inhibitor III - CAS 927827-98-3 - Calbiochem
merck millipore,默克密理博,ABF13,Anti-Interleukin-10 Antibody
merck millipore,默克密理博,AP112F-K,Goat Anti-Human IgG/H&L, Fluorescein (1mg)
