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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE796 描述 Anti-MINA Antibody Alternate Names - ROX
- Ribosomal oxygenase MINA
- Nucleolar protein 52
- Mineral dust-induced gene protein
- MYC-induced nuclear antigen
- Histone lysine demethylase MINA
- 60S ribosomal protein L27a histidine hydroxylase
- Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
背景信息 Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, also known as 60S ribosomal protein L27a histidine hydroxylase or Histone lysine demethylase MINA or MYC-induced nuclear antigen or Nucleolar protein 52 or Ribosomal oxygenase MINA (ROX), and encoded by the gene name MINA or MDIG or MINA53 or NO52, is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-MINA Antibody detects level of MINA & has been published & validated for use in MINA. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected MINA in mouse heart tissue. 生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the N-terminus of human MINA. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman Species Reactivity Note Human, Mouse 抗体类型 Polyclonal Antibody 基因符号 - NO52
- MINA
- MDIG
- MINA53
纯化方法 Antigen Affinity purified UniProt编号 - Q8IUF8
产品使用声明 质量保证 Evaluated by Western Blotting in human heart tissue lysate.
Western Blotting Analysis: 2 μg/mL of this antibody detected MINA in human heart tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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