merck millipore,默克密理博,ABE416,Anti-SHMT1 Antibody

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merck millipore,默克密理博,ABE416,Anti-SHMT1 Antibody
产品名称：Anti-SHMT1 Antibody
产品型号：ABE416
Anti-SHMT1 Antibody is a highly specific sheep polyclonal antibody, that targets Serine hydroxymethyltransferase & has been tested in western blotting.

merck millipore,默克密理博,ABE416,Anti-SHMT1 Antibody

产品介绍

merck millipore,默克密理博,ABE416,Anti-SHMT1 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H	ChIP, WB	Sh	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABE416
描述	Anti-SHMT1 Antibody
Alternate Names	SHMT1 Serine hydroxymethyltransferase, cytosolic SHMT Glycine hydroxymethyltransferase Serine methylase
背景信息	Serine hydroxymethyltransferase (SHMT) is also known as glycine hydroxymethyltransferase or serine methylase, and is an enzyme that catalyzes the reversible conversion of serine and glycine. SHMT is thought to be involved in the epigenetic DNA methylation mechanism and has shown increased activity during cell proliferation and the S phase of the cell cycle. Evidence indicates that SHMT repression is a critical step in the Retinoic Acid-induced cell growth arrest and differentiation pathway.

产品信息
格式	Affinity Purified
控制	Human liver tissue lysate
演示	Purified sheep polyclonal in buffer containing 0.5M HEPES with 0.05% sodium azide and 50% glycerol.

应用
应用	Anti-SHMT1 Antibody is a highly specific sheep polyclonal antibody, that targets Serine hydroxymethyltransferase & has been tested in western blotting.
主要应用	Chromatin Immunoprecipitation (ChIP) Western Blotting
应用说明	Western Blot Analysis: 2.5 µg/mL of this antibody detected SHMT1 in 10 µg of mouse liver tissue lysate (20 µL of antibody at 5 mg/mL is provided. Please take caution to centrifuge and handle carefully, when pipetting from the tube.). Chromatin Immunoprecipitation: A representative lot from an independent laboratory detected SHMT1 when coprecipitated with PCNA in pBABE-Puro-SV50-LT transfected HeLa nuclear extracts. MacFarlane A.J., et al. (2011). J Biol Chem. 286(51):44015-22

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to mouse SHMT1.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Sheep
同种型	IgG
品种反应性	MouseHuman
Species Reactivity Note	Demonstrated to react with Human and Mouse.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_033197
基因符号	Shmt Shmt1
纯化方法	Affinity purified
UniProt编号	P50431

产品使用声明
质量保证	Evaluated by Western Blot in human liver tissue lysate. Western Blot Analysis: 2.5 µg/mL of this antibody detected SHMT1 in 10 µg of human liver tissue lysate (20 µL of antibody at 5 mg/mL is provided. Please take caution to centrifuge and handle carefully, when pipetting from the tube.).
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.