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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ChIP, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 ABE234 描述 Anti-Friend of PRMT1 Antibody Alternate Names - FOP
- Chromatin target of PRMT1 protein
- Friend of PRMT1 protein
- Small arginine- and glycine-rich protein
- SRAG
- Chromatin target of PRMT1
- Friend-of Prmt1
- Chtop
背景信息 The protein called Friend of PRMT1 (FOP), or more correctly Chromatin target of PRMT1 protein, or Small arginine and glycine rich protein (SRAG) is an important partner in estrogen receptor gene activation events and plays a role in 5FMC mediated desumoylation of ZNF148 and the subsequent gene activations of its target genes. Friend of PRMT1 also interacts with other methyltransferases such as PRMT5. The protein is also a component of the dynamic TREX mRNA export complex where it assists in mRNA export. The protein is expressed in the nucleus and contained in the nucleolus of various cell types including erythroid progenitor cells. 产品信息 格式 Serum 演示 Rabbit polyclonal serum with 0.05% sodium azide. 应用 应用 Anti-Friend of PRMT1 Antibody is an antibody against Friend of PRMT1 for use in western blotting & ChIP. 主要应用 - Chromatin Immunoprecipitation (ChIP)
- Western Blotting
应用说明 Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory detected Friend of PRMT1 in MCF-7 cell lysate (Van Dijk, T. B., et al. (2010). Mol Cell Biol. 30(1):260-272.). 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to the C-terminus of human Friend of PRMT1. 表位 C-terminus 宿主 Rabbit 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_056422.2. (Human)
基因符号 - FOP
- CHTOP
- C1orf77
纯化方法 Unpurified UniProt编号 - Q9Y3Y2
产品使用声明 质量保证 Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Friend of PRMT1 in 10 µg of A431 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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