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品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE1404 描述 Anti-MAFA Antibody Alternate Names - V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
- Transcription factor MafA
- Pancreatic beta-cell-specific transcriptional activator
- Transcription factor RIPE3b1
背景信息 MAFA is a tissue specific transcription factor found in the nuclei of pancreas islet beta cells. MAFA specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. MAFA also cooperates synergistically with NEUROD1 and PDX1 in enhancing additional gene expression during development as well. Phosphorylation by GSK3 increases MAFA transcriptional activity and is required for its oncogenic activity. MAFA can be either an oncogene or act as a tumor suppressor, depending on the cell context. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide. 应用 应用 This Anti-MAFA Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of MAFA. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A 1:500 dilution from a representative lot was reported to detect MAFA in HeLa, 293T/17, Capan-2, SAOS-2, SH-SY5Y, and Skin 3, 44 cells. 生物信息 免疫原品种 Mixture of three linear peptides corresponding to amino acids 1-150 of human MAFA. 表位 Region near the N-terminus of MAFA 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 特异性 Recognizes MAFA 品种反应性 Human Species Reactivity Note Human. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_963883
基因符号 - MAFA
纯化方法 Antigen Affinity purified UniProt编号 - Q8NHW3
产品使用声明 质量保证 Evaluated by Western Blotting in a HEK293T cell lysate.
Western Blotting Analysis: A 1 µg/mL dilution of this antibody detected MAFA in a 293T cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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