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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC409 描述 Anti-HSPA2 Antibody Alternate Names - HSPA2
- Heat shock-related 70 kDa protein 2
- Heat shock 70 kDa protein 2
背景信息 The protein named Heat shock-related 70 kDa protein 2, also known as Heat shock 70 kDa protein 2, and encoded by the human gene named HSPA2 is heat shock protein that like other heat shock proteins acts as a molecular chaperone to stabilize preexisting proteins during formation and protect them from aggregation in the cytoplasm. HSPA2 is particularly important in chaperoning proteins associated with sperm, sperm-oocyte recognition and male meiosis. HAPA2 is a testis-specific member of the HSP70 family, and HAPA2 can be localized to the cytoplasm but also is associated with the nucleus and mitochondria depending upon the conditions. While largely testis-specific recent research has found HSPA2 to be expressed in somatic tissues. Moreover, when HSPA2 is expressed in these somatic tissues they are more resistant to several toxic events and anti-cancer drugs. Therefore, HSPA2 is now being examined as a potential target in cancer therapy. EMD-Millipore’s Anti-HSPA2 rabbit polyclonal antibody has been tested in western blots on human ileum tissue extracts and in paraffin embedded immunohistochemistry on human testis tissue sections. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect HSP70 using this rabbit polyclonal antibody, Anti-HSPA2 Antibody validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected HSPA2 in human testis tissue. 生物信息 免疫原品种 GST-tagged fusion protein corresponding to human HSPA2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - HSPA2
纯化方法 Antigen Affinity purified UniProt编号 - P54652
产品使用声明 质量保证 Evaluated by Western Blotting in human ileum tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected HSPA2 in human ileum tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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