merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB874,Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5

  • merck millipore,默克密理博,MAB874,Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5

    产品名称：Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5
    产品型号：MAB874
    Detect Papillomavirus using this Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5 validated for use in IH & WB.

    merck millipore,默克密理博,MAB874,Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5

  • 产品介绍
  • merck millipore,默克密理博,MAB874,Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWB, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB874
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5
    Alternate Names
    • HPV
    背景信息 Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.
    产品信息
    格式 Purified
    控制
    • Human cervical carcinoma extract
    演示 Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
    应用
    应用 Detect Papillomavirus using this Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5 validated for use in IH & WB.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    应用说明 Immunoblotting: Reactive with a 16.5-18 kDa band in reduced westerns of overexpressing cells lines corresponding to HPV E6 protein in cells derived from human cervical carcinoma. {Banks, et al 1987}

    Immunohistochemistry: Shows reactivity on formalin fixed tissue. Dilute with buffer pH 7.5-8.0 to desired working volumes. For extensive dilution, protein containing or other stabilizing medium should be used.

    Immunopreciptiation: Immunoprecipiates 16.5 kDa band from human cervical carcinoma extracts {Banks, et al, 1987}.

    Final working dilutions must be determined by end user.
    生物信息
    免疫原品种 C1P5 was made against HPV type 18 E6 protein produced in bacteria.
    表位 16, 18 E6 protein
    克隆 C1P5
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes Human papilloma virus type 18 early E6 protein. The antibody cross reacts with E6 protein from HPV type 16.
    同种型 IgG
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    纯化方法 Protein A purfied
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB874,Anti-Papillomavirus Antibody, 16, 18 E6 protein, clone C1P5

上一件merck millipore产品：merck millipore,默克密理博,17-10189,LentiBrite ™ GFP-LC3 Control Mutant Lentiviral Biosensor
下一件merck millipore产品：merck millipore,默克密理博,ABC409,Anti-HSPA2 Antibody


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