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  • merck millipore,默克密理博,ABE1065,Anti-acetyl Histone H2B Antibody (Lys5)

  • merck millipore,默克密理博,ABE1065,Anti-acetyl Histone H2B Antibody (Lys5)

    产品名称：Anti-acetyl Histone H2B Antibody (Lys5)
    产品型号：ABE1065
    Detect Histone H2B using this rabbit polyclonal antibody, Anti-acetyl Histone H2B Antibody (Lys5) validated for use in western blotting, Dot Blot, IHC & IP.

    merck millipore,默克密理博,ABE1065,Anti-acetyl Histone H2B Antibody (Lys5)

  • 产品介绍
  • merck millipore,默克密理博,ABE1065,Anti-acetyl Histone H2B Antibody (Lys5)

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBRbSerumPolyclonal Antibody
    描述
    产品目录编号 ABE1065
    描述 Anti-acetyl Histone H2B Antibody (Lys5)
    Alternate Names
    • H2B type 12
    • Histone H2B type 3-B
    背景信息 Histone H2B is one of four histones that form a core octameric structure required for the packaging of DNA into nucleosomes, the most basic level of chromatin arrangement. Histones undergo a number of post-translational modifications (PTM) at their N- and C-terminal tails which can influence chromatin structure and stability; and consequently, transcription, and DNA replication and repair. Acetylation is a reversible PTM that involves the transfer of acetyl groups to N-terminal lysine residues by a family of histone acetyltransferase enzymes, including GNAT, Gcn5, and p300/CBP. Histone acetylation reduces the electrostatic attractions between DNA and histones, which destabilizes chromatin structure and provide transcriptional complexes, for example, with access to DNA, potentially resulting in increased gene transcription.
    产品信息
    格式 Serum
    演示 Rabbit polyclonal serum with 0.05% sodium azide.
    应用
    应用 Detect Histone H2B using this rabbit polyclonal antibody, Anti-acetyl Histone H2B Antibody (Lys5) validated for use in western blotting, Dot Blot, IHC & IP.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Dot Blot (Specificity) Analysis: A 1:1,000 dilution from a representative lot detected acetyl Histone H2B (Lys5) peptides, but not unacetylated Histone H2B (Lys5) peptides or other peptides corresponding to modified histones.

    Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected acetyl Histone H2B (Lys5) in human ileum and kidney tissues.

    Immunoprecipitation Analysis: 10 μL from a representative lot immunoprecipitated acetyl Histone H2B (Lys5) from 500 μg of HeLa acid extract.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of human Histone H2B acetylated at Lys5.
    宿主 Rabbit
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human. Broad species reactivity is expected.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_001019770.1
    基因符号
    • HIST3H2BB
    纯化方法 Unpurified
    UniProt编号
    • Q8N257
    产品使用声明
    质量保证 Evaluated by Western Blotting in sodium butyrate treated HeLa cell lysate.

    Western Blotting Analysis: A 1:2,000 dilution of this antibody detected acetyl Histone H2B (Lys5).
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,ABE1065,Anti-acetyl Histone H2B Antibody (Lys5)

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