merck millipore,默克密理博,ABC404,Anti-ANXA6 Antibody

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merck millipore,默克密理博,ABC404,Anti-ANXA6 Antibody
产品名称：Anti-ANXA6 Antibody
产品型号：ABC404
Anti-ANXA6 Antibody is a highly specific rabbit polyclonal antibody, that targets Annexin & has been tested in western blotting & IHC.

merck millipore,默克密理博,ABC404,Anti-ANXA6 Antibody

产品介绍

merck millipore,默克密理博,ABC404,Anti-ANXA6 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABC404
描述	Anti-ANXA6 Antibody
Alternate Names	p70 Annexin A6 67 kDa calelectrin Annexin VI Annexin-6 Calphobindin-II CPB-II Chromobindin-20 Lipocortin VI Protein III p68
背景信息	The protein Annexin A6 or alternatively known as 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II (CPB-II), Chromobindin-20, Lipocortin VI, Protein III, p68, or p70 and encoded by the human gene named ANXA6 or ANX6. ANXA6 is part of a large family of Annexin proteins and shares with the family the ability to bind negatively charged phospholipids in a calcium dependent manner. Localized in the plasma membrane annexins are important in many cellular functions as the provide scaffolds and play roles in vesicle transport, exocytosis, endocytosis and calcium transport and conduction. Recent research indicates that ANXA6 can interact with PKCalpha and EGFR in A431 cells to help regulate the phosphorylation of pY-EGFR and the associated activation of downstream signaling events associated with cancer. ANXA6 in normal tissue is expressed most strongly in myocardial tissue where it associates with sarcomeric α-actinin and is part of the sarcomere structure. ANXA6 also regulates terminal chondrocyte differentiation by modulating key signaling pathway activities. EMD-Millipore’s Anti-ANXA6 rabbit polyclonal antibody has been tested in western blot on human brain tissue extracts and in paraffin embedded immunohistochemistry on human colon cancer tissue sections.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Anti-ANXA6 Antibody is a highly specific rabbit polyclonal antibody, that targets Annexin & has been tested in western blotting & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected ANXA6 in human colon cancer tissue.

生物信息
免疫原品种	Histidine-tagged fusion protein corresponding to human ANXA6.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	MouseHuman
抗体类型	Polyclonal Antibody
基因符号	ANX6 ANXA6
纯化方法	Antigen Affinity purified
UniProt编号	P08133

产品使用声明
质量保证	Evaluated by Western Blotting in mouse brain tissue lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected ANXA6 in mouse brain tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.