merck millipore,默克密理愽
  • merck millipore,默克密理博,557353,RORγ Inverse Agonist, SR2211 - Calbiochem

  • merck millipore,默克密理博,557353,RORγ Inverse Agonist, SR2211 - Calbiochem

    产品名称：RORγ Inverse Agonist, SR2211 - Calbiochem
    产品型号：557353
    The RORγ Inverse Agonist, SR2211 controls the biological activity of RORγ.

    merck millipore,默克密理博,557353,RORγ Inverse Agonist, SR2211 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,557353,RORγ Inverse Agonist, SR2211 - Calbiochem

    重要规格表

    经验配方
    C₂₆H₂₄F₇N₃O
    描述
    概述 A cell-permeable, piperazine containing biphenyl compound that binds directly to retinoic acid receptor related orphan receptor γ (RORg) and acts as a highly selective and inverse agonist (Ki = 105 nM; IC50 ~ 320 nM). Reported to block the transcriptional activity of RORg and suppress the synthesis of IL-17 in EL-4 murine lymphoma cell line. Exhibits only a minimal effect on RORa and LXRa activity.
    产品目录编号 557353
    品牌系列 Calbiochem®
    同义词 1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol, SR-2211, SR 2211
    参考
    参考 Kumar, N., et al. 2012. ACS Chem. Biol. 7, 672.
    产品信息
    形式 White powder
    Hill配方 C₂₆H₂₄F₇N₃O
    化学配方 C₂₆H₂₄F₇N₃O
    Molar Mass 527.5
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,557353,RORγ Inverse Agonist, SR2211 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,PICM01250,Millicell 插入式细胞培养皿, 12 mm, 亲水性 PTFE, 0.4 µm
下一件merck millipore产品：merck millipore,默克密理博,420120,Juglone - CAS 481-39-0 - Calbiochem


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