• merck millipore,默克密理博,475872,MnTMPyP - Calbiochem
  • merck millipore,默克密理博,475872,MnTMPyP - Calbiochem

    产品名称:MnTMPyP - Calbiochem
    产品型号:475872
    Cell-permeable superoxide dismutase (SOD) mimetic.

    merck millipore,默克密理博,475872,MnTMPyP - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,475872,MnTMPyP - Calbiochem

    重要规格表

    经验配方
    C₇₂H₆₅MnN₈O₁₃S₄
    描述
    概述 Cell-permeable superoxide dismutase (SOD) mimetic. Catalyzes the dismutation of O2– • (rate constant ~4 x 107 M-1 s-1) even in the presence of excess EDTA. Can substitute for SOD in mutants of E. coli lacking this enzyme. MnTMPyP acts in vivo as an NADPH/GSH:O2 oxidoreductase rather than as an SOD mimetic. Also an efficient peroxynitrite reductase when redox-coupled with biological antioxidants.
    产品目录编号 475872
    品牌系列 Calbiochem®
    同义词 Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin, Tetratosylate, Hydroxide
    参考
    参考 Izbicka, E., et al. 1999. Cancer Res. 59, 639.
    Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 6053.
    Gardner, P.R., et al. 1996. Arch. Biochem. Biophys. 325, 20.
    Liochev, S.I., and Fridovich, I. 1995. Arch. Biochem. Biophys. 321, 271.
    Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471.
    产品信息
    具有ATP竞争性 N
    形式 Black solid
    Hill配方 C₇₂H₆₅MnN₈O₁₃S₄
    化学配方 C₇₂H₆₅MnN₈O₁₃S₄
    Molar Mass 1433.5
    可逆 N
    结构配方图像
    生物信息
    主靶 Superoxide dismutase (SOD) mimetic
    纯度 ≥95% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,475872,MnTMPyP - Calbiochem

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