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经验配方 C₇₂H₆₅MnN₈O₁₃S₄ 描述 概述 Cell-permeable superoxide dismutase (SOD) mimetic. Catalyzes the dismutation of O2– • (rate constant ~4 x 107 M-1 s-1) even in the presence of excess EDTA. Can substitute for SOD in mutants of E. coli lacking this enzyme. MnTMPyP acts in vivo as an NADPH/GSH:O2• oxidoreductase rather than as an SOD mimetic. Also an efficient peroxynitrite reductase when redox-coupled with biological antioxidants. 产品目录编号 475872 品牌系列 Calbiochem®
同义词 Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin, Tetratosylate, Hydroxide 参考 参考 Izbicka, E., et al. 1999. Cancer Res. 59, 639.
Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 6053.
Gardner, P.R., et al. 1996. Arch. Biochem. Biophys. 325, 20.
Liochev, S.I., and Fridovich, I. 1995. Arch. Biochem. Biophys. 321, 271.
Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471.产品信息 具有ATP竞争性 N 形式 Black solid Hill配方 C₇₂H₆₅MnN₈O₁₃S₄ 化学配方 C₇₂H₆₅MnN₈O₁₃S₄ Molar Mass 1433.5 可逆 N 结构配方图像 生物信息 主靶 Superoxide dismutase (SOD) mimetic 纯度 ≥95% by TLC 理化信息 细胞可渗透 Y 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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