merck millipore,默克密理愽
  • merck millipore,默克密理博,420120,Juglone - CAS 481-39-0 - Calbiochem

  • merck millipore,默克密理博,420120,Juglone - CAS 481-39-0 - Calbiochem

    产品名称：Juglone - CAS 481-39-0 - Calbiochem
    产品型号：420120
    A highly selective cell-permeable, irreversible inhibitor of PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family).

    merck millipore,默克密理博,420120,Juglone - CAS 481-39-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420120,Juglone - CAS 481-39-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀H₆O₃481-39-0
    描述
    概述 A highly selective cell-permeable, irreversible inhibitor of PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family). Other known PPlase inhibitors such as cyclosporin A, FK506, and rapamycin are not reported to inhibit the parvulin family of PPlases. The inactivation is shown to occur via the addition of thiol groups to juglone and not by any redox process. Exhibits bacteriostatic and fungistatic effects. Reported to be cytotoxic towards eukaryotic cells and to block transcription by RNA polymerase II.
    产品目录编号 420120
    品牌系列 Calbiochem®
    同义词 5-Hydroxy-1,4-naphthlenedione, 5-Hydroxy-p-naphthoquinone
    参考
    参考 Chao, S.H., et al. 2001. Nucleic Acids Res. 29, 767.
    Hennig, L., et al. 1998. Biochemistry 37, 5953.
    产品信息
    CAS号 481-39-0
    具有ATP竞争性 N
    形式 Orange solid
    Hill配方 C₁₀H₆O₃
    化学配方 C₁₀H₆O₃
    Molar Mass 174.2
    可逆 N
    结构配方图像
    生物信息
    主靶 PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family)
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    GHS安全信息
    RTECS QJ5775000
    安全信息
    R相 R: 36/37/38-25

    Irritating to eyes, respiratory system and skin.
    Toxic if swallowed.
    S相 S: 45-26

    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Toxic
    有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420120,Juglone - CAS 481-39-0 - Calbiochem

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