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品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB2212 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-phospho GluR4 (S862) Antibody 背景信息 Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. Direct phosphorylation of GluR4-containing receptors may regulate rapid excitatory synaptic transmission. In addition, phosphorylation of GluR4 S862. is both necessary and sufficient to deliver the receptor to the synapse and induce plasticity in early postnatal development. 产品信息 格式 Serum 控制 - Rat Brain Cerebellum lysate
演示 Serum with 0.05% NaN3 应用 应用 Anti-phospho GluR4 (S862) Antibody is an antibody against phospho GluR4 (S862) for use in WB. 主要应用 - Western Blotting
应用说明 Western Blot Analysis:
Cat. # AB2212 recognizes pGluR4 (S862) at 1:5,000 in rat brain cerebellum Lysate.生物信息 免疫原品种 Synthetic peptide from rat. 宿主 Rabbit 特异性 Cat. # AB2212 recognzies phospho GluR4 (S862). 品种反应性 Rat Species Reactivity Note Rat. May react with mouse, human, primate and dog based on sequence homology. Reactivity with other species has not been tested. 抗体类型 Polyclonal Antibody 基因符号 - GluR-D
- GRIA4
- GLURD
- GluR-4
修改 - Phosphorylation
UniProt编号 - P19493
产品使用声明 质量保证 Routinely tested on rat brain cerebellum lysate. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt. 包装信息 数量 50µL
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