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品种反应性 主要应用 宿主 格式 抗体类型 R, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC342 描述 Anti-KPNA2 Antibody Alternate Names - SRP1-alpha
- Karyopherin alpha nucleoprotein interactor 2
- Importin alpha2
- IPOA1
- RAG cohort protein 1
- QIP2
- Karyopherin subunit alpha-2
背景信息 Karyopherin alpha nucleoprotein interactor 2 (KPNA2), also known as Importin alpha-2, RAG cohort protein 1 (RCH1), SRP1-alpha QIP2 (SRP1), is the alpha subunit 2 of karyopherin which functions as a cargo carrier that transports various complexes from cytoplasm into nucleus and forms a complex with importin subunit beta-1 and. KPNA2 is expressed ubiquitously and contains one IBB/importin beta domain, ten Armadillo repeats and three intervening nuclear localization sequences (NLSs). Recent studies have shown that KPNA2 plays an important role in tumorigenesis and tumor progression. KPNA2 is a heterodimer with KPNB1. It has been implied to interact with HIV-1 Vpr, PLAG1, ANP32E, ARL4A, CTNNBL1, NBN and APEX1 (via N-terminus). KPNA2 is also a component of a complex containing CSE1L, RAN and KPNA2 and interacts directly with CSE1L. 产品信息 格式 Affinity Purified 控制 - Rat heart tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Detect Importin using this rabbit polyclonal antibody, Anti-KPNA2 Antibody validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected KPNA2 in human heart tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human KPNA2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHuman 抗体类型 Polyclonal Antibody 基因符号 - SRP1
- KPNA2
- RCH1
纯化方法 Antigen Affinity purified UniProt编号 - P52292
产品使用声明 质量保证 Evaluated by Western Blotting in rat heart tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected KPNA2 in 15 µg of rat heart tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,MABF351,Anti-TNF-α (human) Antibody, FITC, clone MAb11
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