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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC322 描述 Anti-UQCRFS1 Antibody Alternate Names - UQCRFS1
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Complex III subunit 5
- Cytochrome b-c1 complex subunit 5
- Rieske iron-sulfur protein
- RISP
- Ubiquinol-cytochrome c reductase iron-sulfur subunit
- Complex III subunit IX
- Ubiquinol-cytochrome c reductase 8 kD
背景信息 The protein named Cytochrome b-c1 complex subunit Rieske, mitochondrial or alternatively Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Rieske iron-sulfur protein, (RISP) or Ubiquinol-Cytochrome C reductase iron-sulfur subunit, and encoded by the human gene named UCRFS1, is part of a huge multi-protein complex called Complex III or Cytochrome B-C1 complex which is the respiratory chain that generates the electrochemical potential needed to produce ATP for cellular metabolism. The UCRFS1 protein gets cleaved into the active transit peptide called Cytochrome b-c1 complex subunit 11 or Complex III subunit IX or Ubiquinol-cytochrome C reductase 8 kDa protein. Complex III contains 11 subunits and 3 respiratory subunits. It is located in the mitochondrion inner membrane and it contains iron and sulfur so it is part of the iron-sulfur protein complex within the mitochondria. UQCRFS1 is a key subunit of the bc1 complex (Complex III) and it is often amplified in many cancers at the gene level in more aggressive forms, likely due to the need for increased ATP production. EMD-Millipore’s Anti-UQCRFS1 rabbit polyclonal antibody has been tested in western blots on mouse ovary tissue extracts. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-UQCRFS1 antibody detects level of UQCRFS1 & has been published & validated for use in UQCRFS1. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged fusion protein corresponding to human UQCRFS1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Mouse 抗体类型 Polyclonal Antibody 基因符号 - UQCRFS1
纯化方法 Antigen Affinity purified UniProt编号 - P47985
产品使用声明 质量保证 Evaluated by Western Blotting in mouse ovary tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected UQCRFS1 in mouse ovary tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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