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经验配方 CAS号 C₁₆₅H₂₆₁N₅₁O₅₅S₂ 122384-88-7 描述 概述 A 37-amino acid polypeptide secreted by the β cells of the pancreas. Structurally related to calcitonin. Has anorectic effects in rats. Implicated in the development of type II diabetes through its modulation of peripheral effects of insulin. Blocks the activation of glycogen synthase by insulin. 产品目录编号 05-23-2540 品牌系列 Calbiochem®
同义词 Islet Amyloid Polypeptide 参考 参考 Baque, S., et al. 1994. Biochem. J. 304, 449.
Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.产品信息 CAS号 122384-88-7 具有ATP竞争性 N 声明 Not for sale in the United States. 形式 White to off-white lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₆₅H₂₆₁N₅₁O₅₅S₂ 化学配方 C₁₆₅H₂₆₁N₅₁O₅₅S₂ Molar Mass 3903.4 肽序列 H-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7) 可逆 N 基于肽含量售出 Yes
生物信息 主靶 Has anorectic effects in rats 纯度 ≥97% by HPLC 理化信息 细胞可渗透 N 溶解度 5% Acetic Acid 肽含量 Yes
肽序列 H-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7) 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
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