• merck millipore,默克密理博,05-23-2540,Amylin, Human - CAS 122384-88-7 - Calbiochem
  • merck millipore,默克密理博,05-23-2540,Amylin, Human - CAS 122384-88-7 - Calbiochem

    产品名称:Amylin, Human - CAS 122384-88-7 - Calbiochem
    产品型号:05-23-2540
    A 37-amino acid polypeptide secreted by the β cells of the pancreas.

    merck millipore,默克密理博,05-23-2540,Amylin, Human - CAS 122384-88-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,05-23-2540,Amylin, Human - CAS 122384-88-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆₅H₂₆₁N₅₁O₅₅S₂122384-88-7
    描述
    概述 A 37-amino acid polypeptide secreted by the β cells of the pancreas. Structurally related to calcitonin. Has anorectic effects in rats. Implicated in the development of type II diabetes through its modulation of peripheral effects of insulin. Blocks the activation of glycogen synthase by insulin.
    产品目录编号 05-23-2540
    品牌系列 Calbiochem®
    同义词 Islet Amyloid Polypeptide
    参考
    参考 Baque, S., et al. 1994. Biochem. J. 304, 449.
    Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
    Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
    Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.
    产品信息
    CAS号 122384-88-7
    具有ATP竞争性 N
    声明 Not for sale in the United States.
    形式 White to off-white lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₁₆₅H₂₆₁N₅₁O₅₅S₂
    化学配方 C₁₆₅H₂₆₁N₅₁O₅₅S₂
    Molar Mass 3903.4
    肽序列 H-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7)
    可逆 N
    基于肽含量售出 Yes
    生物信息
    主靶 Has anorectic effects in rats
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 5% Acetic Acid
    肽含量 Yes
    肽序列 H-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7)
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

    merck millipore,默克密理博,05-23-2540,Amylin, Human - CAS 122384-88-7 - Calbiochem

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