• merck millipore,默克密理博,121800,Advanced Glycation Endproduct-BSA
  • merck millipore,默克密理博,121800,Advanced Glycation Endproduct-BSA

    产品名称:Advanced Glycation Endproduct-BSA
    产品型号:121800
    AGE-BSA has been reported to induce apoptosis in cultured human umbilical vein endothelial cells and inhibit nitric oxide synthase activity in proximal tubular epithelial cells.

    merck millipore,默克密理博,121800,Advanced Glycation Endproduct-BSA

  • 产品介绍
  • merck millipore,默克密理博,121800,Advanced Glycation Endproduct-BSA

    描述
    概述 Prepared by reacting BSA with glycoaldehyde under sterile conditions. Glycated-BSA shows a 5,000 - 10,000% increase in fluorescence as compared to normal BSA (confirmed by fluorescence spectrophotometry, excitation/emission 370/440 nm). AGE-BSA has been reported to induce apoptosis in cultured human umbilical vein endothelial cells and inhibit nitric oxide synthase activity in proximal tubular epithelial cells. Advanced glycation end products and their receptors have been implicated in the pathogenesis of diabetes, induction of proinflammatory cytokines, and stimulation of smooth muscle proliferation, and fibronectin production.
    产品目录编号 121800
    品牌系列 Calbiochem®
    同义词 AGE-BSA
    参考
    参考 Okamoto, T., et al. 2002. Microvasc. Res. 63, 186.
    Ohgami, N., et al. 2001. J. Biol. Chem. 276, 3195.
    Wang, R., et al. 2001. J. Nippon Med. Sch. 68, 472.
    Sakata, N., et al. 2000. J. Atheroscler. Thromb. 7, 169.
    Verbeke, P., et al. 2000. Biochim. Biophys. Acta 1502, 481.
    Farboud, B., et al. 1999. Mol. Vis. 5, 11.
    Huang, J.-S., et al. 1999. Biochem. J. 342, 231.
    Min, C., et al. 1999. Diabetes Res. Clin. Pract. 46, 197.
    Neumann, A., et al. 1999. FEBS Lett. 453, 283.
    Stitt, A.W., et al. 1999. Biochem. Biophys. Res. Commun. 256, 549.
    Nazaimoon, W. and Bak, K. 1998. Malays. J. Pathol. 20, 83.
    产品信息
    形式 Liquid
    配方 In sterile-filtered PBS.
    生物信息
    纯度 ≥95% by SDS-PAGE
    浓缩标签 Please refer to vial label for lot-specific concentration
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,121800,Advanced Glycation Endproduct-BSA

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