merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT414,Anti-Moesin Antibody, clone 38/87

  • merck millipore,默克密理博,MABT414,Anti-Moesin Antibody, clone 38/87

    产品名称：Anti-Moesin Antibody, clone 38/87
    产品型号：MABT414
    Detect Moesin using this mouse monoclonal antibody, Anti-Moesin Antibody, clone 38/87 validated for use in western blotting, Flow Cytometry, IP & IHC.

    merck millipore,默克密理博,MABT414,Anti-Moesin Antibody, clone 38/87

  • 产品介绍
  • merck millipore,默克密理博,MABT414,Anti-Moesin Antibody, clone 38/87

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    B, HIHC, WB, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT414
    描述 Anti-Moesin Antibody, clone 38/87
    Alternate Names
    • Membrane-organizing extension spike protein
    • Moesin
    背景信息 Moesin (membrane-organizing extension spike protein) is the protein encoded by the MSN gene. Moesin is a member of the ERM (ezrin, moesin, radixin) family of proteins that regulate linkage between the plasma membrane and the actin cytoskeleton. Thus, moesin is a peripheral membrane protein that is keenly involved in the signaling and structural connections in cytoskeletal plasma membrane structures like microvilli. Moesin in its active, phosphorylated state strongly binds actin and helps anchor it to the plasma membrane. Moesin is localized to filopodia and other membranous extensions of various cell types and thus plays a role in cell-cell recognition signaling, cell movement, and cell transport. In its inactive, non-phosphorylated state, Moesin binds itself in a head-tail fashion and is incapable of binding actin or other cytoskeletal proteins. The kinase ROCK2 is central to the opening up of moesin and allowing its interaction with actin and the plasma membrane.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Moesin using this mouse monoclonal antibody, Anti-Moesin Antibody, clone 38/87 validated for use in western blotting, Flow Cytometry, IP & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    • Flow Cytometry
    应用说明 Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected Moesin in 10 µg of HL-60 cell lysate.

    Flow Cytometry Analysis: 4 µg from a representative lot detected Moesin in 1X10E6 HeLa cells.

    Flow Cytometry Analysis: A representative lot from an independent laboratory detected Moesin in THP-1, U937, and MOLT-4 cells (Takamatsu, H., et al. (2009). J Immunol. 182(1):703-710.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Moesin in purified heparain-binding proteins, and from human renal cortex tisssue (Lankes, W., et al. (1988). Biochem J. 251(3):831-842.).

    Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Moesin in HT-29 cell lysate (Lankes, W., et al. (1988). Biochem J. 251(3):831-842.).

    Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Moesin in certain human brain tissues (Johnson, M. W., et al. (2002). Acta Neuropathol. 104(2):188-196.).
    生物信息
    免疫原品种 Recombinant protein corresponding to bovine Moesin.
    克隆 38/87
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 BovineHuman
    Species Reactivity Note Demonstrated to react with Human and Bovine.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001039942
    基因符号
    • MSN
    纯化方法 Protein G purified
    UniProt编号
    • Q2HJ49
    产品使用声明
    质量保证 Evaluated by Western Blotting in HL-60 cell lysate.

    Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected Moesin in 10 µg of HL-60 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABT414,Anti-Moesin Antibody, clone 38/87

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