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  • merck millipore,默克密理博,AB9780-200UL,Anti-TWIK-1 Antibody

  • merck millipore,默克密理博,AB9780-200UL,Anti-TWIK-1 Antibody

    产品名称：Anti-TWIK-1 Antibody
    产品型号：AB9780-200UL
    This Anti-TWIK-1 Antibody is validated for use in IH, WB for the detection of TWIK-1.

    merck millipore,默克密理博,AB9780-200UL,Anti-TWIK-1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB9780-200UL,Anti-TWIK-1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB9780-200UL
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-TWIK-1 Antibody
    Alternate Names
    • K<sub>2p</sub>1.1, KCNK1, Inward rectifying K+ channel TWIK-1
    • K<sub>2p</sub>1.1
    • KCNK1
    产品信息
    格式 Affinity Purified
    控制
    • Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
    演示 Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
    应用
    应用 This Anti-TWIK-1 Antibody is validated for use in IH, WB for the detection of TWIK-1.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    应用说明 Western blot: 1:200 using ECL on rat brain lysate and 1:300 on HEK-TWIK-1 transfected cells.
    Immunohistochemistry on rat brain sections.
    Dilutions should be made using a carrier protein such as BSA (1-3%).
    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Purified peptide from amino acids 53-69 of human TWIK-1 (Accession number O00180).
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes TWIK-1 (K2p1.1, KCNK1, Inward rectifying K+ channel TWIK-1).
    品种反应性 RatMouse
    Species Reactivity Note The immunogen sequence is identical in human and porcine.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002245.2
    Entrez基因汇总 This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
    基因符号
    • KCNO1
    • KCNK1
    • K2p1.1
    • HOHO1
    • TWIK-1
    • TWIK1
    • HOHO
    • DPK
    纯化方法 Immunoaffinity purified
    UniProt编号
    • O00180
    UniProt汇总 FUNCTION: SwissProt: O00180 # Weakly inward rectifying potassium channel.
    SIZE: 336 amino acids; 38143 Da
    SUBUNIT: Homodimer (Potential).
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
    TISSUE SPECIFICITY: Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney.
    SIMILARITY: SwissProt: O00180 ## Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
    MISCELLANEOUS: Inhibited by barium, quinine, quinidine and internal acidification. Activated by protein kinase C.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 200 µL

    merck millipore,默克密理博,AB9780-200UL,Anti-TWIK-1 Antibody

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