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  • merck millipore,默克密理博,AB9473,Anti-Prostaglandin E2 Receptor EP3 Antibody

  • merck millipore,默克密理博,AB9473,Anti-Prostaglandin E2 Receptor EP3 Antibody

    产品名称：Anti-Prostaglandin E2 Receptor EP3 Antibody
    产品型号：AB9473
    This Anti-Prostaglandin E2 Receptor EP3 Antibody is validated for use in IH(P) for the detection of Prostaglandin E2 Receptor EP3.

    merck millipore,默克密理博,AB9473,Anti-Prostaglandin E2 Receptor EP3 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB9473,Anti-Prostaglandin E2 Receptor EP3 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIH(P)RbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB9473
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Prostaglandin E2 Receptor EP3 Antibody
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
    应用
    应用 This Anti-Prostaglandin E2 Receptor EP3 Antibody is validated for use in IH(P) for the detection of Prostaglandin E2 Receptor EP3.
    主要应用
    • Immunohistochemistry (Paraffin)
    应用说明 Immunohistochemistry on formalin fixed paraffin embedded tissue sections.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide from the C-terminus of human Prostaglandin E Receptor EP3.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes Prostaglandin E Receptor EP3.
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_198719.1
    • NM_000957.2
    • NM_198712.2
    • NM_198713.1
    • NM_198714.1
    • NM_198715.2
    • NM_198716.1
    • NM_198717.1
    • NM_198718.1
    Entrez基因汇总 The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.
    基因符号
    • EP3-IV
    • PTGER3
    • EP3-III
    • EP3-I
    • PGE2-R
    • MGC141829
    • EP3-II
    • EP3
    • EP3e
    • MGC27302
    • MGC141828
    UniProt编号
    • P43115
    UniProt汇总 FUNCTION: SwissProt: P43115 # Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
    SIZE: 390 amino acids; 43310 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Expressed at least in small intestine, heart and pancreas.
    SIMILARITY: SwissProt: P43115 ## Belongs to the G-protein coupled receptor 1 family.
    产品使用声明
    销售限制 This product is not available for sale in Japan.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB9473,Anti-Prostaglandin E2 Receptor EP3 Antibody

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