merck millipore,默克密理愽
  • merck millipore,默克密理博,573108,STAT5 Inhibitor - CAS 285986-31-4 - Calbiochem

  • merck millipore,默克密理博,573108,STAT5 Inhibitor - CAS 285986-31-4 - Calbiochem

    产品名称：STAT5 Inhibitor - CAS 285986-31-4 - Calbiochem
    产品型号：573108
    The STAT5 Inhibitor, also referenced under CAS 285986-31-4, controls the biological activity of STAT5.

    merck millipore,默克密理博,573108,STAT5 Inhibitor - CAS 285986-31-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,573108,STAT5 Inhibitor - CAS 285986-31-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₁N₃O₃285986-31-4
    描述
    概述 A cell-permeable nonpeptidic nicotinoyl hydrazone compound that selectively targets the SH2 domain of STAT5 (IC50 = 47 µM against STAT5b SH2 domain EPO peptide binding activity), while exhibiting much less effect towards the SH2 domain of STAT1, STAT3, or Lck (IC50 >500 µM). Shown to block STAT5/STAT5 DNA binding activity in K562 nuclear extract and inhibit IFN-α-stimulated STAT5, but not STAT1 or STAT3, tyrosine phosphorylation in Daudi cells.
    产品目录编号 573108
    品牌系列 Calbiochem®
    同义词 Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide
    参考
    参考 Muller, J., et al. 2008. ChemBioChem 9, 723.
    产品信息
    CAS号 285986-31-4
    形式 White solid
    Hill配方 C₁₆H₁₁N₃O₃
    化学配方 C₁₆H₁₁N₃O₃
    Molar Mass 293.3
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573108,STAT5 Inhibitor - CAS 285986-31-4 - Calbiochem

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