merck millipore,默克密理愽
  • merck millipore,默克密理博,AB6019,Anti-Thymosin beta-4 Antibody

  • merck millipore,默克密理博,AB6019,Anti-Thymosin beta-4 Antibody

    产品名称：Anti-Thymosin beta-4 Antibody
    产品型号：AB6019
    Anti-Thymosin beta-4 Antibody is an antibody against Thymosin beta-4 for use in WB & IC.

    merck millipore,默克密理博,AB6019,Anti-Thymosin beta-4 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB6019,Anti-Thymosin beta-4 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MICC, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB6019
    描述 Anti-Thymosin beta-4 Antibody
    Alternate Names
    • T beta-4
    • thymosin beta 4, X-linked
    • prothymosin beta-4
    • thymosin, beta 4
    • thymosin, beta 4, X chromosome
    背景信息 Thymosin beta-4 is the most prevalent of the cytoplasmic G-actin binding proteins belonging to the highly conserved thymosin beta family. Known to bind actin monomers, Thymosin beta-4 sequesters G-actin in a manner that prevents actin polymerization. Thymosin beta-4 plays several important roles including induction of tissue remodeling, wound healing in both cell and tissue injuries, and cell differentiation via mechanisms that have yet to be fully elucidated. It is involved in the regulation of the cytoskeleton, and thereby influences an array of cellular processes. Within the brain, Thymosin beta-4 is associated with the neurite extension and migration of neurons. Expression has been observed in various hemopoietic and lymphoid malignant cell lines.
    产品信息
    格式 Affinity Purified
    控制
    • Recombinant Thymosin beta-4
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Thymosin beta-4 Antibody is an antibody against Thymosin beta-4 for use in WB & IC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Western Blot (Snap i.d.®) Analysis: 1 µg/mL from a previous lot detected Thymosin beta-4 on 10 µg of recombinant Thymosin beta-4.

    Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected Thymosin beta-4 in NIH/3T3, HeLa, and A431 cells.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to the internal domain of human Thymosin beta-4.
    表位 Unknown
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Th antibody recognizes the internal domain of Thymosin beta-4.
    品种反应性 RatHumanMouse
    Species Reactivity Note Demonstrated to react with human and mouse. Predicted to react with rat based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_066932
    基因符号
    • Fx
    • FX
    • TB4X
    • TMSB4
    • THYB4
    • PTMB4
    • TMSB4X
    纯化方法 Affinity purified
    UniProt编号
    • P62328
    UniProt汇总 FUNCTION: Plays an important role in the organization of the cytoskeleton (by similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.

    Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase (by similarity).

    SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton.

    TISSUE SPECIFICTY: Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.

    INDUCTION: By alpha interferons. Decreased levels in THP-1 cells after treatment with recombinant interferon-lambda.

    SEQUENCE SIMILARITIES: Belongs to the thymosin beta family.
    产品使用声明
    质量保证 Evaluated by Western Blot in recombinant Thymosin beta-4.

    Western Blot Analysis: 1 µg/mL of the antibody detected Thymosin beta-4 on 10 µg of recombinant Thymosin beta-4.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB6019,Anti-Thymosin beta-4 Antibody

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