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merck millipore,默克密理博,AB5818-200UL,Anti-Potassium Channel Kir4.1 Antibody
产品名称：Anti-Potassium Channel Kir4.1 Antibody
产品型号：AB5818-200UL
Detect Potassium Channel Kir4.1 using this Anti-Potassium Channel Kir4.1 Antibody validated for use in WB.
merck millipore,默克密理博,AB5818-200UL,Anti-Potassium Channel Kir4.1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB5818-200UL 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Potassium Channel Kir4.1 Antibody 产品信息 格式 Affinity Purified 控制 - CONTROL ANTIGEN: Included free of charge with the antibody is 20 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile distilled water. For negative control, preincubate 1 μg of protein with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
演示 Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). 应用 应用 Detect Potassium Channel Kir4.1 using this Anti-Potassium Channel Kir4.1 Antibody validated for use in WB. 主要应用 - Western Blotting
应用说明 Western blot: 1:400 using ECL on rat brain membranes.
Dilutions should be made using a carrier protein such as BSA (1-3%)
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide corresponding to amino acids 356-375 of rat, mouse or human Kir4.1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Kir4.1. The epitope does not share homology with any other known proteins. 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002241.3
Entrez基因汇总 This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. 基因符号 - BIRK-10
- KCNJ10
- KIR1.2
- Kir4.1
- KCNJ13-PEN
- Kir1.2
- KIR4.1
UniProt编号 - P78508
UniProt汇总 FUNCTION: SwissProt: P78508 # May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).
SIZE: 379 amino acids; 42508 Da
SUBUNIT: Seems to form heterodimer with Kir5.1/KCNJ16. Interacts with INADL (By similarity).
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P78508 ## Belongs to the inward rectifier-type potassium channel family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 200 µL
上一件merck millipore产品：merck millipore,默克密理博,119134,Adenosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 73536-95-5 - Calbiochem
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