- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
主要应用 可用的分析物 检测方法 KA PKC Radioactive 描述 产品目录编号 17-139 品牌系列 Upstate
商名 - Upstate
描述 PKC Assay Kit 产品信息 部件 - P81 Phosphocellulose Squares (Cat.# 20-134)
- PKA/CaMK Inhibitor Cocktail (Cat.# 20-132)
- PKC Substrate Cocktail (Cat.# 20-131)
- Assay Dilution Buffer II (ADBII) (Cat.# 20-111)
- PKC Lipid Activator (Cat.# 20-133)
- Magnesium/ATP Cocktail (Cat.# 20-113)
检测方法 Radioactive 应用 应用 The radioactive PKC Assay Kit is designed to measure the phosphotransferase activity of protein kinase C (PKC) in immunoprecipitates & column fractions. 主要应用 - Kinase Assay
生物信息 可用的分析物 - PKC
Entrez基因编号 - NM_002737.2
Entrez基因汇总 Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. 基因符号 - PKC-alpha
- PRKCA
- PKC-A
- PKCA
- MGC129901
- AAG6
- MGC129900
- PRKACA
UniProt编号 - P05129
- P17252
- P05771
UniProt汇总 FUNCTION: SwissProt: P17252 # PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domain (By similarity).
SIZE: 672 amino acids; 76764 Da
SUBUNIT: Interacts with CENTA1, CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine.
SIMILARITY: SwissProt: P17252 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 C2 domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.产品使用声明 质量保证 Routinely evaluated by phosphorylation of PKC substrate peptide. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 1 kit
上一件merck millipore产品：merck millipore,默克密理博,ABT294,Anti-ZMPSTE24 Antibody
下一件merck millipore产品：merck millipore,默克密理博,MAB1948P,Anti-Heparan Sulfate Proteoglycan (Perlecan) Antibody, clone A7L6
相关产品
merck millipore,默克密理博,04-397,Anti-PDGF Receptor Beta (CT) Antibody, clone Y92, rabbit monoclonal
merck millipore,默克密理博,MABT219,Anti-Actin Antibody, clone JLA20
merck millipore,默克密理博,264101,Deoxycholic Acid, Sodium Salt - CAS 302-95-4 - Calbiochem
merck millipore,默克密理博,ABT294,Anti-ZMPSTE24 Antibody
merck millipore,默克密理博,MAB1948P,Anti-Heparan Sulfate Proteoglycan (Perlecan) Antibody, clone A7L6
merck millipore,默克密理博,MABT212,Anti-Nebulin Antibody, clone 9H7.1
merck millipore,默克密理博,AB5818-200UL,Anti-Potassium Channel Kir4.1 Antibody
merck millipore,默克密理博,SLAA033SS,Millex-AA，0.80 µm，混合纤维素酯，33 mm，环氧乙烷灭菌