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品种反应性 主要应用 宿主 格式 抗体类型 Ch, H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT219 Replaces 04-1040 描述 Anti-Actin Antibody, clone JLA20 Alternate Names - Alpha-actin-1
- Actin, alpha skeletal muscle
背景信息 Actin is an abundantly expressed in eukaryotic cells and it is the core component of the cytoskeleton. It exists in three isoforms: alpha actin, which is found in muscle tissue and forms fibrous actin that facilitates muscle contractility; and beta and gamma actin which are found in non-muscle cells and facilitate cell motility. Actin exists initially as globular actin (G-actin) which is converted to filamentous actin (F-actin) upon assembly. The formation of F-actin is a complex multistep process that is tightly regulated by signaling from the actin-binding proteins (ABPs) and Rho family GTPases. Filamentous actin is crosslinked with other actin polymers to form a complex cytoskeletal network which is required for exo- and phagocytosis, vesicular trafficking, cell migration, and gene regulation, among other cellular processes. 产品信息 格式 Purified 控制 - SK-BR3 cell lysate
演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. 应用 应用 Detect Actin using this Anti-Actin Antibody, clone JLA20 validated for use in Western Blotting, Immunofluorescence. 主要应用 - Western Blotting
应用说明 Immunofluorescence Analysis: A representative lot was used by an independent laboratory in NRK cells. (Cao, L.G., et al. (1993). The Journal of Cell Biology. 123(1):173-181.)
Western Blot Analysis: A representative lot was used by an independent laboratory in Me4405 melanoma cell lysate. (Thomas, W.D., et al. (2000). Journal of Immunology. 165:5612–5620.)生物信息 免疫原品种 Chicken cytoskeletal proteins 克隆 JLA20 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgMκ 品种反应性 ChickenHuman Species Reactivity Note Demonstrated to react with Human. Predicted to react with Chicken based on immunogen design. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001026234
基因符号 - ACTA
- ACTA1
纯化方法 Purified by ion exchange chromatography UniProt编号 - P68139
产品使用声明 质量保证 Evaluated by Western Blot in SK-BR3 cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Actin on 10 µg of SK-BR3 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,04-397,Anti-PDGF Receptor Beta (CT) Antibody, clone Y92, rabbit monoclonal
下一件merck millipore产品：merck millipore,默克密理博,494461,n-Octyl-β-D-thioglucopyranoside, ULTROL Grade - CAS 85618-21-9 - Calbiochem
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