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品种反应性 主要应用 宿主 格式 抗体类型 Fe, Ch, H, M, R ICC Ch Serum Polyclonal Antibody 描述 产品目录编号 AB5733 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Vimentin Antibody 产品信息 格式 Serum 控制 - Breast carcinoma tissue, Colon, Prostate, Tonsil, Tonsilar lymphoma, Uterus, Ureter
演示 Chicken IgY in PBS with 5 mM sodium azide as a preservative. 应用 应用 Detect Vimentin using this Anti-Vimentin Antibody validated for use in IC. 主要应用 - Immunocytochemistry
应用说明 Immunocytochemistry: 1:1,000-1:5,000
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant vimentin. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Chicken 特异性 Recognizes Vimentin. 品种反应性 FelineChickenHumanMouseRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003380.2
Entrez基因汇总 Along with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin (MIM 125660) is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.[supplied by OMIM] 基因符号 - vimentin
- VIM
- FLJ36605
- Vimentin.
纯化方法 Unpurified UniProt编号 - P08670
UniProt汇总 FUNCTION: SwissProt: P08670 # Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
SIZE: 466 amino acids; 53652 Da
SUBUNIT: Homopolymer. Component of a complex composed at least of ACTB, AP2M1, AP2A1, AP2A2, MEGF10 and VIM. Interacts with HCV core protein.
TISSUE SPECIFICITY: Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone- independent mammary carcinoma cell lines.
PTM: One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.
SIMILARITY: SwissProt: P08670 ## Belongs to the intermediate filament family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 50 µL
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