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品种反应性 主要应用 宿主 格式 抗体类型 R, B, Ch, M WB, ELISA, ICC, IHC Rb Purified Polyclonal Antibody 描述 产品目录编号 AB5620 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Neurogranin Antibody 产品信息 格式 Purified 控制 - Brain tissue
演示 Purified immunoglobulin. Purified by ammonium sulfate precipitation. Liquid in PBS with 0.02% sodium azide as a preservative. 应用 应用 This Anti-Neurogranin Antibody is validated for use in ELISA, IC, IH, IP, WB for the detection of Neurogranin. 主要应用 - Western Blotting
- ELISA
- Immunocytochemistry
- Immunohistochemistry
应用说明 Immunoblot: > 1:500-1:000
Immunohistochemistry: > 1:1,000 on 4% paraformaldehyde / PBS fixed or 3% Paraformaldehyde / 0.1% Gluteraldehyde / PBS fixed tissue sections.
Immunocytochemistry: > 1:1,000.
Immunoprecipitation: > 1:100
ELISA: > 1:2,000
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant rat Neurogranin (complete sequence). 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Neurogranin. 品种反应性 RatBovineChickenMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_006176.1
Entrez基因汇总 Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. 基因符号 - hng
- NRGN
- neurogranin
- Ng
- Neurogranin
- RC3
纯化方法 Ammonium sulfate precipitation UniProt编号 - Q92686
UniProt汇总 FUNCTION: SwissProt: Q92686 # Acts as a third messenger substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).
SIZE: 78 amino acids; 7618 Da
SIMILARITY: SwissProt: Q92686 ## Belongs to the neurogranin family. & Contains 1 collagen-like domain. & Contains 1 IQ domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 100 µL
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