merck millipore,默克密理愽
  • merck millipore,默克密理博,324674,EGFR Inhibitor - CAS 879127-07-8 - Calbiochem

  • merck millipore,默克密理博,324674,EGFR Inhibitor - CAS 879127-07-8 - Calbiochem

    产品名称：EGFR Inhibitor - CAS 879127-07-8 - Calbiochem
    产品型号：324674
    The EGFR Inhibitor, also referenced under CAS 879127-07-8, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation application More>>

    merck millipore,默克密理博,324674,EGFR Inhibitor - CAS 879127-07-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,324674,EGFR Inhibitor - CAS 879127-07-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₁H₁₈F₃N₅O879127-07-8
    描述
    概述 A cell-permeable 4,6-dianilinopyrimidine compound that acts as a potent, ATP-competitive, and highly selective inhibitor of EGFR and some EGFR mutants (IC50 = 21 nM, 63 nM, and 4 nM for EGFRwt, EGFRL858R and EGFRL861Q, respectively) vs. erbB4/Her4 (IC50 = 7.64 µM) and a panel of 55 other kinases. Shown to completely block EGF-induced EGFR autophosphorylation in U-2OS cells at 10 µM.
    产品目录编号 324674
    品牌系列 Calbiochem®
    同义词 Cyclopropanecarboxylic acid-(3-(6-(3-trifluoromethyl-phenylamino)-pyrimidin-4-ylamino)-phenyl)-amide
    参考
    参考 Zhang, Q., et al. 2006. J. Am. Chem. Soc. 128, 2182
    产品信息
    CAS号 879127-07-8
    具有ATP竞争性 Y
    形式 Off-white solid
    Hill配方 C₂₁H₁₈F₃N₅O
    化学配方 C₂₁H₁₈F₃N₅O
    Molar Mass 413.4
    可逆 N
    结构配方图像
    生物信息
    主靶 EGFR
    主靶IC50 21 nM, 63 nM, and 4 nM for EGFRwt, EGFRL858R and EGFRL861Q, respectively
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,324674,EGFR Inhibitor - CAS 879127-07-8 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,23-044M,VHL Protein Complex, Active, 250 µg
下一件merck millipore产品：merck millipore,默克密理博,71186,YeastBuster™ Protein Extraction Reagent


相关产品

merck millipore,默克密理博,CC127,Caspase 2, recombinant human active merck millipore,默克密理博,CC127,Caspase 2, recombinant human active

merck millipore,默克密理博,AB5620,Anti-Neurogranin Antibody merck millipore,默克密理博,AB5620,Anti-Neurogranin Antibody

merck millipore,默克密理博,IHCR1015-6,Anti-Tau-1 Antibody, prediluted, clone PC1C6 merck millipore,默克密理博,IHCR1015-6,Anti-Tau-1 Antibody, prediluted, clone PC1C6

merck millipore,默克密理博,ASK07,p53 Antibody Sampler Kit merck millipore,默克密理博,ASK07,p53 Antibody Sampler Kit

merck millipore,默克密理博,23-044M,VHL Protein Complex, Active, 250 µg merck millipore,默克密理博,23-044M,VHL Protein Complex, Active, 250 µg

merck millipore,默克密理博,71186,YeastBuster™ Protein Extraction Reagent merck millipore,默克密理博,71186,YeastBuster™ Protein Extraction Reagent

merck millipore,默克密理博,MAB3584,Anti-Heterochromatin Protein-1 α Antibody, clone 2HP-1H5 merck millipore,默克密理博,MAB3584,Anti-Heterochromatin Protein-1 α Antibody, clone 2HP-1H5

merck millipore,默克密理博,17-10260,ChIPAb+™ N-CoR Antibody merck millipore,默克密理博,17-10260,ChIPAb+™ N-CoR Antibody

merck millipore,默克密理博,HTMP1MAG-54K,MILLIPLEX MAP Human TIMP Magnetic Bead Panel 1 - Immunology Multiplex Assay merck millipore,默克密理博,HTMP1MAG-54K,MILLIPLEX MAP Human TIMP Magnetic Bead Panel 1 - Immunology Multiple...

merck millipore,默克密理博,14-346M,CHK1 Protein, active, 250 µg merck millipore,默克密理博,14-346M,CHK1 Protein, active, 250 µg


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部