• merck millipore,默克密理博,AB5656P,Anti-Histamine Receptor 2 Antibody, CT
  • merck millipore,默克密理博,AB5656P,Anti-Histamine Receptor 2 Antibody, CT

    产品名称:Anti-Histamine Receptor 2 Antibody, CT
    产品型号:AB5656P
    Detect Histamine Receptor 2 using this Anti-Histamine Receptor 2 Antibody, C-terminus validated for use in ELISA & WB.

    merck millipore,默克密理博,AB5656P,Anti-Histamine Receptor 2 Antibody, CT

  • 产品介绍
  • merck millipore,默克密理博,AB5656P,Anti-Histamine Receptor 2 Antibody, CT

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5656P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Histamine Receptor 2 Antibody, CT
    Alternate Names
    • H2R
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in 100 mM Tris, pH 7.5, containing 0.2% BSA and 0.05% sodium azide.
    应用
    应用 Detect Histamine Receptor 2 using this Anti-Histamine Receptor 2 Antibody, C-terminus validated for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 μg/mL using ECL. Recognizes a ~69kDa band in reducing westerns.

    ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 14 amino acid peptide sequence within the cytoplasmic, C-terminus of rat HR2 (Ruat et al. 1991; Kobayashi et al. 1996; Murakami et al. 1999; Ganz

    et al. 1991; Nihsi et al. 1995;

    Orange et al. 1996).
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes rat Histamine Receptor 2 (HR2). The immunogen shows no significant sequence homology with other histamine receptors.

    SPECIES REACTIVITIES: The immunogen peptide is 100% conserved in mouse. No significant homology with human HR2. Reactivity with other species has not been confirmed.
    品种反应性 RatMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_022304.1
    Entrez基因汇总 Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation.
    基因符号
    • H2R
    • HRH2
    • DDX15
    • DBP1
    UniProt编号
    • P25021
    UniProt汇总 FUNCTION: SwissProt: P25021 # The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
    SIZE: 359 amino acids; 40098 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    SIMILARITY: SwissProt: P25021 ## Belongs to the G-protein coupled receptor 1 family.
    MISCELLANEOUS: Antagonists for this receptor have proven to be effective therapy for acid peptic disorders of the gastrointestinal tract. Certain antagonists are used in the treatment of neuropsychiatric and neurological diseases such as schizophrenia, Alzheimer disease and Parkinson disease.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB5656P,Anti-Histamine Receptor 2 Antibody, CT

上一件merck millipore产品:merck millipore,默克密理博,SF-3200,SOD1; Human, Cyanine 5 RNA Detection Probe,SmartFlare
下一件merck millipore产品:merck millipore,默克密理博,420291,IPTG, Animal-Free, High Purity - CAS 367-93-1 - Calbiochem



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