merck millipore,默克密理愽
  • merck millipore,默克密理博,AB15085,Anti-Huntingtin associated protein 1B Antibody

  • merck millipore,默克密理博,AB15085,Anti-Huntingtin associated protein 1B Antibody

    产品名称：Anti-Huntingtin associated protein 1B Antibody
    产品型号：AB15085
    Anti-Huntingtin associated protein 1B Antibody detects level of Huntingtin associated protein 1B & has been published & validated for use in WB, IH.

    merck millipore,默克密理博,AB15085,Anti-Huntingtin associated protein 1B Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB15085,Anti-Huntingtin associated protein 1B Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RIHC, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB15085
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Huntingtin associated protein 1B Antibody
    Alternate Names
    • HAP1B
    产品信息
    格式 Affinity Purified
    演示 Liquid in PBS with 0.1% sodium azide.
    应用
    应用 Anti-Huntingtin associated protein 1B Antibody detects level of Huntingtin associated protein 1B & has been published & validated for use in WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Western blot: 0.5-1 μg/mL on extracts from rat brain lysate. Immunohistochemistry on brain sections.

    Immunohistochemistry: 1:100-1:1,000 on 4% paraformaldehyde fixed rat brain tissue sectioned at 50 microns and processed free floating.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide
    宿主 Rabbit
    特异性 Huntingtin associated protein 1B (HAP1B). By Western blot the antibody recognizes a band at ~110 kDa in rat brain lysate. The band is completed abolished after incubating the antibody with the immunogen peptide.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_177977.2
    • NM_001079870.1
    • NM_001079871.1
    • NM_003949.3
    Entrez基因汇总 Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    基因符号
    • HLP
    • HAP1
    • HLP1
    • HAP2
    • HAP-1
    • hHLP1
    • HIP5
    纯化方法 Immunoaffinity purified
    UniProt编号
    • P54257
    UniProt汇总 FUNCTION: SwissProt: P54257 # Associates specifically with huntingtin. This binding is enhanced by an expanded polyglutamine repeat.
    SIZE: 671 amino acids; 75514 Da
    TISSUE SPECIFICITY: Predominantly expressed in brain. Selectively expressed in neurons.
    SIMILARITY: SwissProt: P54257 ## Contains 1 HAP1 N-terminal domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB15085,Anti-Huntingtin associated protein 1B Antibody

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