merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5652P,Anti-Histamine Receptor 1 Antibody, CT

  • merck millipore,默克密理博,AB5652P,Anti-Histamine Receptor 1 Antibody, CT

    产品名称：Anti-Histamine Receptor 1 Antibody, CT
    产品型号：AB5652P
    This Anti-Histamine Receptor 1 Antibody, C-terminus is validated for use in ELISA, WB for the detection of Histamine Receptor 1.

    merck millipore,默克密理博,AB5652P,Anti-Histamine Receptor 1 Antibody, CT

  • 产品介绍
  • merck millipore,默克密理博,AB5652P,Anti-Histamine Receptor 1 Antibody, CT

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, MWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5652P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Histamine Receptor 1 Antibody, CT
    Alternate Names
    • H1R
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.
    应用
    应用 This Anti-Histamine Receptor 1 Antibody, C-terminus is validated for use in ELISA, WB for the detection of Histamine Receptor 1.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 μg/mL using ECL. Recognizes a 57kDa band representing the H1 receptor

    ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 17 amino acid peptide sequence near the cytoplasmic, C-terminus of rat HR1 (Fujimoto et al. 1993; Inoue et al. 1996; DeBacker et al. 1993; Fukui et al. 1994; Moguilevsky et al. 1994).
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes rat Histamine Receptor 1 (HR1). The immunogen shows no significant sequence homology with other histamine receptors.

    The immunogen peptide is 100% conserved in mouse and bovine, 94% in human, fish and monkey and 80% in guinea pig. Reactivity with other species has not been confirmed.
    品种反应性 RatBovineMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001098213.1
    • NM_000861.3
    • NM_001098211.1
    • NM_001098212.1
    Entrez基因汇总 Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
    基因符号
    • H1-R
    • HRH1
    • hisH1
    UniProt编号
    • P35367
    UniProt汇总 FUNCTION: SwissProt: P35367 # In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
    SIZE: 487 amino acids; 55784 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    PTM: Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.
    SIMILARITY: SwissProt: P35367 ## Belongs to the G-protein coupled receptor 1 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB5652P,Anti-Histamine Receptor 1 Antibody, CT

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