merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5474-50UL,Anti-Calcium Channel Antibody, Voltage Gated γ2

  • merck millipore,默克密理博,AB5474-50UL,Anti-Calcium Channel Antibody, Voltage Gated γ2

    产品名称：Anti-Calcium Channel Antibody, Voltage Gated γ2
    产品型号：AB5474-50UL
    Detect Calcium Channel using this Anti-Calcium Channel Antibody, Voltage Gated γ2 validated for use in IH & WB.

    merck millipore,默克密理博,AB5474-50UL,Anti-Calcium Channel Antibody, Voltage Gated γ2

  • 产品介绍
  • merck millipore,默克密理博,AB5474-50UL,Anti-Calcium Channel Antibody, Voltage Gated γ2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5474-50UL
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Calcium Channel Antibody, Voltage Gated γ2
    Alternate Names
    • Stargazin
    • Cag3
    产品信息
    格式 Affinity Purified
    控制
    • CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
    演示 Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
    应用
    应用 Detect Calcium Channel using this Anti-Calcium Channel Antibody, Voltage Gated γ2 validated for use in IH & WB.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    应用说明 Western blot: 1:200 using ECL

    Immunohistochemistry

    Dilutions should be made using a carrier protein such as BSA (1-3%)

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A purified peptide corresponding to amino acid residues 213-228 of human Ca-gamma-2 (Accesssion # 088602) with additional N-terminal cysteine.
    表位 Voltage Gated gamma2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes Ca-gamma-2 protein. The epitope is not similar to any other known proteins.

    SPECIES REACTIVITIES: The immunogen sequence is 100% conserved with human and mouse. Other species have not been tested.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_006078.2
    Entrez基因汇总 L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which have been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family.
    基因符号
    • MGC138504
    • CACNG2
    • MGC138502
    • stargazin
    UniProt编号
    • Q9Y698
    UniProt汇总 FUNCTION: SwissProt: Q9Y698 # Thought to stabilize the calcium channel in an inactivated (closed) state.
    SIZE: 323 amino acids; 35966 Da
    SUBUNIT: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Interacts with the PDZ domains of DLG4/PSD-95 and DLG1/SAP97. May interact with GOPC (By similarity).
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Brain.
    PTM: Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4.
    SIMILARITY: SwissProt: Q9Y698 ## Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB5474-50UL,Anti-Calcium Channel Antibody, Voltage Gated γ2

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