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  • merck millipore,默克密理博,AB5403,Anti-NMDAR2B Antibody, phosphoTyr 1472

  • merck millipore,默克密理博,AB5403,Anti-NMDAR2B Antibody, phosphoTyr 1472

    产品名称：Anti-NMDAR2B Antibody, phosphoTyr 1472
    产品型号：AB5403
    Anti-NMDAR2B Antibody, phosphoTyr 1472 is an antibody against NMDAR2B for use in WB.

    merck millipore,默克密理博,AB5403,Anti-NMDAR2B Antibody, phosphoTyr 1472

  • 产品介绍
  • merck millipore,默克密理博,AB5403,Anti-NMDAR2B Antibody, phosphoTyr 1472

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5403
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-NMDAR2B Antibody, phosphoTyr 1472
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl with 100 μg/mL BSA, 50% glycerol and 0.09% sodium azide.
    应用
    应用 Anti-NMDAR2B Antibody, phosphoTyr 1472 is an antibody against NMDAR2B for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:1,000

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide corresponding to amino acids surrounding the phosphoTyr1472 of rat NMDAR2B.
    表位 phosphoTyr 1472
    宿主 Rabbit
    特异性 NMDAR2B, phosphoTyr1472. The antibody recognizes a protein of ~180 kDa in Western blot. The labeling of the NMDAR2B protein in Western blots of rat brain is blocked by the phosphopeptide but not by the dephosphopeptide. Two additional lower molecular weight bands are present in Western blots of rat brain.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_000834.2
    Entrez基因汇总 N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
    基因符号
    • hNR3
    • GRIN2B
    • MGC142180
    • Glutamate
    • NR2B
    • NMDAR2B
    • NR3
    • MGC142178
    修改
    • Phosphorylation
    UniProt编号
    • Q13224
    UniProt汇总 FUNCTION: SwissProt: Q13224 # NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
    SIZE: 1484 amino acids; 166367 Da
    SUBUNIT: Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Found in a complex with GRIN1 and GRIN3B. Found in a complex with GRIN1, GRIN3A and PPP2CB. Interacts with PDZ domains of INADL and DLG4 (By similarity).
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.
    SIMILARITY: SwissProt: Q13224 ## Belongs to the glutamate-gated ion channel (TC 1.A.10) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB5403,Anti-NMDAR2B Antibody, phosphoTyr 1472

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