merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5398,Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, CT

  • merck millipore,默克密理博,AB5398,Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, CT

    产品名称：Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, CT
    产品型号：AB5398
    Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, C-terminus detects level of Vanilloid Receptor Like Protein 1 & has been published & validated for use in IH.

    merck millipore,默克密理博,AB5398,Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, CT

  • 产品介绍
  • merck millipore,默克密理博,AB5398,Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, CT

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RIHCRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB5398
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, CT
    Alternate Names
    • VRL-1
    产品信息
    格式 Serum
    演示 Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.
    应用
    应用 Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, C-terminus detects level of Vanilloid Receptor Like Protein 1 & has been published & validated for use in IH.
    主要应用
    • Immunohistochemistry
    应用说明 Immunohistochemistry: 1:1,000-1:2,000 on rat dorsal root ganglia.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Peptide corresponding to the C-terminal 18 amino acids of the rat VRL-1 protein sequence (Acc#: AAD26364). This immunogen sequence is 100% conserved in the mouse growth factor regulated calcium channel (Acc#: AB021665)
    表位 C-terminus
    宿主 Rabbit
    特异性 Vanilloid receptor like protein 1 (VRL-1). Immunohistochemical analysis of rat dorsal root ganglia and spinal cord indicates that this antibody is of high specificity.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_016113.3
    Entrez基因汇总 This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat.
    基因符号
    • VRL1
    • TRPV2
    • VRL
    • TrpV2
    • VRL-1
    • OTRPC2
    • MGC12549
    非反应性品种
    • Human
    UniProt编号
    • Q9Y5S1
    UniProt汇总 FUNCTION: SwissProt: Q9Y5S1 # Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
    SIZE: 764 amino acids; 85981 Da
    SUBUNIT: Homotetramer (Probable). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3. Interacts with RGA (By similarity).
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Cytoplasm (By similarity). Melanosome. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    PTM: N-glycosylated (By similarity). & Phosphorylated by PKA (By similarity).
    SIMILARITY: SwissProt: Q9Y5S1 ## Belongs to the transient receptor family. TrpV subfamily. & Contains 3 ANK repeats.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material at -20°C to -70°C for up to 6 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB5398,Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, CT

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