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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB4330 描述 Anti-DDX4 (Vasa) Antibody Alternate Names - DEAD box protein 4
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
- probable ATP-dependent RNA helicase DDX4
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4
- Vasa homolog
背景信息 DDX4 (Vasa or MVH) is a member of the DEAD family of proteins and is a probable ATP-dependent RNA helicase. DDX4 (Vasa) proteins are mostly localized in testicular germ cells in the cytoplasm of spermatocytes. DDX4 (Vasa) is a high-copy extragenic suppressor gene. DDX4 (Vasa) is shown to be significantly decreased in spermatozoa of men that are infertile and may have an important role in male fertility. 产品信息 格式 Affinity Purified 控制 - Mouse testis tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. 应用 应用 Anti-DDX4 (Vasa) Antibody detects level of DDX4 (Vasa) & has been published & validated for use in WB, IH(P). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:100-250 dilution from a previous lot detected DDX4 (Vasa) in normal human testis tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of mouse DDX4 (Vasa). 表位 C-terminus 宿主 Rabbit 特异性 This antibody recognizes DDX4 (Vasa) at the C-terminus. 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with human, mouse, and rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_034159
基因符号 - DDX4
- VASA
- MVH
纯化方法 Affinity Purified UniProt编号 - Q61496
UniProt汇总 FUNCTION: May play a role in germ cell development.
CATALYTIC ACTIVITY: ATP + H2O = ADP + phosphate.
SUBUNIT STRUCTURE: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. N-terminus interacts with RANBP9. Interacts with PIWIL2 and MAEL. Ref.3 SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm › perinuclear region.
TISSUE SPECIFICTY: Testis.
DEVELOPMENTAL STAGE: Expressed in spermatogenic cells from the spermatocyte stage to the round spermatid stage.
SEQUENCE SIMILARITIES: Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.产品使用声明 质量保证 Evaluated by Western Blot in mouse testis tissue lysate.
Western Blot Analysis: A 1:500 dilution of this antibody detected DDX4 (Vasa) in 10 µg of mouse testis tissue lysate. Western Blot performed without Tween.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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