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主要应用 品种 Uni Prot编号 EA Human Q8WTS6 描述 产品目录编号 03-209 品牌系列 Upstate
商名 - Upstate
描述 SET7/9 human recombinant - Methyltransferase enzyme 概述 Human recombinant SET7/9 expressed in E. Coli 背景信息 The methylation of histones plays a pivotal role in the regulation of chromatin structure and gene expression. Histone methylation can occur on Arg or Lys residues, with an exquisite site selectivity for Lys methylation at specific positions in the N-termini of histones H3 and H4. SET7/9, a histone methyltransferase (HMTase), which transfers methyl groups to Lys4 of Histone H3, forms a complex with S-adenosyl-L-methionine. This complex contains an active site consisting of a binding pocket where an AdoMet molecule, in an unusual conformation, binds a narrow substrate-specific channel that only unmethylated lysine residues can access, and a catalytic tyrosine residue. 产品信息 格式 Purified 演示 In liquid containing 50 mM Tris-HCl, pH 7.5, containing 0.2 M sodium chloride, 5 mM DTT and 20% glycerol. 应用 应用 Human recombinant SET7/9 expressed in E. Coli. 主要应用 - Enzyme Assay
应用说明 Methyltransferase assays 生物信息 浓缩 1 mg/mL 纯度 Purity >95% by SDS-PAGE 品种 Human 特异活性 <1.0EU/µg protein (LAL test) 物理形式 Frozen solution UniProt编号 - Q8WTS6
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 12 months at -20°C from date of receipt. Avoid multiple freeze/thaw cycles. 包装信息 数量 100 µg
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