merck millipore,默克密理博,MABE466,Anti-Nucleolin, clone EPR7952, Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABE466,Anti-Nucleolin, clone EPR7952, Rabbit Monoclonal Antibody
产品名称：Anti-Nucleolin, clone EPR7952, Rabbit Monoclonal Antibody
产品型号：MABE466
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,MABE466,Anti-Nucleolin, clone EPR7952, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABE466,Anti-Nucleolin, clone EPR7952, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABE466
描述	Anti-Nucleolin, clone EPR7952, Rabbit Monoclonal Antibody
Alternate Names	Protein C23 Nucleolin
背景信息	Nucleolin, also known as Protein C23, and encoded by the gene name NCL, is the major nucleolar protein of exponentially growing eukaryotic cells. It is a ubiquitous conserved multi-domain phosphoprotein found in all vertebrate species. Nucleolin contains a specific bipartite nuclear localization signal sequence and three different structural domains. Nucleolin is a multifunctional protein involved in most steps of ribosome biogenesis. Nucleolin has been implicated in chromatin structure, rDNA transcription, rRNA maturation, ribosome assembly, cytokinesis, nucleogenesis, cell proliferation and growth, and nucleo-cytoplasmic transport. Nucleolin also exhibits autodegradation, DNA and RNA helicase activities, and DNA-dependent ATPase activity. Nucleolin activities may be regulated by proteolysis, methylation, ADPribosylation, and phosphorylation by several kinases, including casein kinase II (CK2), p34cdc2, and protein kinase C-ζ.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:250-500 dilution from a representative lot detected Nucleolin in human colon tissue. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human Nucleolin.
克隆	EPR7952
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
基因符号	NCL
纯化方法	Unpurified
UniProt编号	P19338

产品使用声明
质量保证	Evaluated by Western Blotting in Fetal brain, K562 and HuT-78 lysates. Western Blotting Analysis: A 1:10,000-50,000 dilution of this antibody detected Nucleolin in Fetal brain, K562 and HuT-78 lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.