merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5511,Anti-Opioid Receptor Antibody, µ, pain

  • merck millipore,默克密理博,AB5511,Anti-Opioid Receptor Antibody, µ, pain

    产品名称：Anti-Opioid Receptor Antibody, µ, pain
    产品型号：AB5511
    Detect Opioid Receptor using this Anti-Opioid Receptor Antibody, µ, pain validated for use in IC, IH & WB.

    merck millipore,默克密理博,AB5511,Anti-Opioid Receptor Antibody, µ, pain

  • 产品介绍
  • merck millipore,默克密理博,AB5511,Anti-Opioid Receptor Antibody, µ, pain

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Pm, H, M, RWB, ICC, IHCRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB5511
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Opioid Receptor Antibody, µ, pain
    Alternate Names
    • opioid receptor, mu 1
    • mu opiate receptor
    • mu opiate receptor
    背景信息 Opiates derived from the opium poppy, Papaver somniferum, have been used for millenia for their anti-diarrheal, analgesic and euphoric properties. More recently, endogenous peptides, enkephalins, dynorphins, and endorphins, were found to bind to the same sites as opiate alkaloids. The receptors for the classical opioids are three related GPCRs, δ, κ, and µ (also known as OP1, OP2 and OP3, respectively), that activate Gi/o to reduce intracellular cAMP levels. Although most clinically used opioids function by activation of the µ opioid receptor, agonists of spinal δ opioid receptors have antinociceptive activity that is independent of µ. In addition, activation of δ increases locomotor activity, inhibits gastrointestinal motility, and decreases respiratory frequency (Dhawan et al., 1996). Agonists for δ opioid receptors also exhibit antidepressant-like activity in animal models (Broom et al., 2002).
    产品信息
    格式 Serum
    控制
    • Spinal cord, liver lysate
    演示 Rabbit polyclonal serum in buffer containing 0.05% sodium azide.
    应用
    应用 Detect Opioid Receptor using this Anti-Opioid Receptor Antibody, µ, pain validated for use in IC, IH & WB.
    主要应用
    • Western Blotting
    • Immunocytochemistry
    • Immunohistochemistry
    应用说明 Immunohistochemistry:
    1:2,500-1:5,000 dilution of a previous lot was used.

    Western blot:
    1:1,000 dilution of a previous lot was used.

    Immunocytochemistry:
    1:2,500-1:5,000 dilution of a previous lot was used.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide from the C-terminus of rat Mu Opioid receptor.
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Mu Opioid receptor.
    品种反应性 PrimateHumanMouseRat
    Species Reactivity Note Human, rat, mouse and primate. Other species have not been tested.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_000914.2
    基因符号
    • KIAA0403
    • OPRM1
    • MOR
    • MOR-1
    • MOR1
    • OPRM
    纯化方法 Unpurified
    UniProt编号
    • P35372
    UniProt汇总 FUNCTION: SwissProt: P35372 # Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin.
    SIZE: 400 amino acids; 44779 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    SIMILARITY: SwissProt: P35372 ## Belongs to the G-protein coupled receptor 1 family.
    产品使用声明
    质量保证 Evaluated by Western Blot on Human Liver lysate.

    Western Blot Analysis:
    1:500 dilution of this antibody detected Opioid Receptor on 10 µg of Human Liver lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20ºC from date of receipt.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB5511,Anti-Opioid Receptor Antibody, µ, pain

上一件merck millipore产品：merck millipore,默克密理博,MABE466,Anti-Nucleolin, clone EPR7952, Rabbit Monoclonal Antibody
下一件merck millipore产品：merck millipore,默克密理博,UFC800308,Amicon Ultra-4，PLBC Ultracel-3 超滤膜，3 kDa


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