merck millipore,默克密理愽
  • merck millipore,默克密理博,AB3540P,Anti-Monocarboxylate Transporter 1 Antibody

  • merck millipore,默克密理博,AB3540P,Anti-Monocarboxylate Transporter 1 Antibody

    产品名称：Anti-Monocarboxylate Transporter 1 Antibody
    产品型号：AB3540P
    Detect Monocarboxylate Transporter 1 using this Anti-Monocarboxylate Transporter 1 Antibody validated for use in ELISA & WB.

    merck millipore,默克密理博,AB3540P,Anti-Monocarboxylate Transporter 1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB3540P,Anti-Monocarboxylate Transporter 1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB3540P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Monocarboxylate Transporter 1 Antibody
    Alternate Names
    • MCT1
    产品信息
    格式 Affinity Purified
    演示 Liquid in PBS containing 0.1% BSA .
    应用
    应用 Detect Monocarboxylate Transporter 1 using this Anti-Monocarboxylate Transporter 1 Antibody validated for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-5 μg/mL using ECL. Membrane preps are recommended.



    ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 17 amino acid peptide sequence near the C-terminus of rat MCT1 (Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999).
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes rat Monocarboxylate Transporter 1 (MCT1). The immunogen shows no significant sequence homology with MCT2-8.

    SPECIES REACTIVITIES: The immunogen sequence is 93% conserved in hamster, 80% in mouse and only 40% in human. Reactivity with other species has not been confirmed.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_003051.3
    Entrez基因汇总 The SLC16A1 gene encodes a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT (Garcia et al., 1994 [PubMed 8124722]).[supplied by OMIM]
    基因符号
    • MCT1
    • SLC16A1
    • MCT
    • FLJ36745
    • MGC44475
    UniProt编号
    • P53985
    UniProt汇总 FUNCTION: SwissProt: P53985 # Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
    SIZE: 500 amino acids; 53958 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Widely expressed in normal and in cancer cells.
    DISEASE: SwissProt: P53985 # Defects in SLC16A1 are the cause of symptomatic deficiency in lactate transport (SDLT) [MIM:245340]; also known as erythrocyte lactate transporter defect. Deficiency of lactate transporter may result in an acidic intracellular environment created by muscle activity with consequent degeneration of muscle and release of myoglobin and creatine kinase. This defect might compromise extreme performance in otherwise healthy individuals.
    SIMILARITY: SwissProt: P53985 ## Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB3540P,Anti-Monocarboxylate Transporter 1 Antibody

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