merck millipore,默克密理愽
  • merck millipore,默克密理博,AB2257,Anti-Vesicular GABA Transporter Antibody

  • merck millipore,默克密理博,AB2257,Anti-Vesicular GABA Transporter Antibody

    产品名称：Anti-Vesicular GABA Transporter Antibody
    产品型号：AB2257
    Anti-Vesicular GABA Transporter Antibody is an antibody against Vesicular GABA Transporter for use in WB, IH.

    merck millipore,默克密理博,AB2257,Anti-Vesicular GABA Transporter Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB2257,Anti-Vesicular GABA Transporter Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RIHC, WBRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB2257
    描述 Anti-Vesicular GABA Transporter Antibody
    Alternate Names
    • vesicular inhibitory amino acid transporter
    • solute carrier family 32, member 1
    • solute carrier family 32 (GABA vesicular transporter), member 1
    • Vesicular GABA transporter
    • Solute carrier family 32 member 1
    • GABA and glycine transporter
    • solute carrier family 32
    背景信息 Vesicular GABA transporter (VGAT), the first vesicular amino acid transporter to be molecularly identified, differs in structure from previously cloned vesicular neurotransmitter transporters and defines a novel gene family. VGAT is highly concentrated in the nerve endings of GABAergic neurons in the brain and spinal cord but also in glycinergic nerve endings. In contrast, hippocampal mossy fiber boutons, which are glutamatergic but known to contain GABA, lack VGAT immunoreactivity. Although the great majority of nerve terminals containing GABA or glycine are immunopositive for VGAT, subpopulations of nerve endings rich in GABA or glycine appear to lack the protein. Additional vesicular transporters or alternative modes of release may therefore contribute to the inhibitory neurotransmission mediated by these two amino acids.
    产品信息
    格式 Serum
    控制
    • Rat brain lysate.
    演示 Rabbit polyclonal serum in buffer containing 0.1M Tris-Glycine (pH7.4) 15mM NaCl with 0.05% NaN3.
    应用
    应用 Anti-Vesicular GABA Transporter Antibody is an antibody against Vesicular GABA Transporter for use in WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis:
    1:50 - 1:500 dilution from a previous lot detected vesiluar GABA transporter using IHC-Select Detection with HRP-DAB.
    生物信息
    免疫原品种 KLH conjugated Vesicular GABA Transporter corresponding to the C-terminus.
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Cat. # AB2257 recognizes VGAT.
    品种反应性 Rat
    Species Reactivity Note Rat. Predicted to react with human, rat and monkey.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_080552.2
    Entrez基因汇总 The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II. [provided by RefSeq]
    基因符号
    • hVIAAT
    • OTTHUMP00000030977
    • VGAT
    • VIAAT
    • bA122O1.1
    纯化方法 Antigen affinity purified
    UniProt编号
    • Q9H598
    UniProt汇总 FUNCTION: Involved in the uptake of GABA and glycine into the synaptic vesicles.

    SUBCELLULAR LOCATION:Cytoplasmic vesicle membrane; Multi-pass membrane proteinBy similarity.

    TISSUE SPECIFICITY: Retina. Expressed throughout the horizontal cells or more specifically at the terminals. Ref.5

    SEQUENCE SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
    产品使用声明
    质量保证 Routinely evaluated by Western Blot on rat brain lysates.

    Western Blot Analysis:
    1:500 - 1:1,000 dilution of this lot detected vesicular GABA transporter on 10 µg of rat brain lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8ºC from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB2257,Anti-Vesicular GABA Transporter Antibody

上一件merck millipore产品：merck millipore,默克密理博,IPVH08100,Immobilon-P PVDF 0.45 µm 8 x 10 cm sheet
下一件merck millipore产品：merck millipore,默克密理博,AB5441,Anti-Tropomyosin Antibody


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