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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB19011 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Tenascin Antibody Alternate Names - Tenascin C
背景信息 Tenascin is known to play an active role in development of central nervous system and mesenchymal-derived organs, exist in the vasculature of tumors in adults, and function in cell adhesion. 产品信息 格式 Affinity Purified 演示 Affinity purified using immobilized human tenascin; presented as a liquid in PBS containing no preservatives. 应用 应用 This Anti-Tenascin Antibody is validated for use in WB, IH(P) for the detection of Tenascin. 主要应用 - Western Blotting
应用说明 Western blot: 0.5 - 1.0 μg/mL; recognizes 250-350 kDa polypeptides in reduced samples.
Immunohistochemistry: 10 to 20 μg/mL in paraffin embedded tissues
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Purified human tenascin from glioma culture supernatant. 宿主 Rabbit 特异性 Reacts strongly with tenascin from human and mouse in both Western blotting and immunohistochemistry. While it has not been tested, it should also react strongly in these applications with tenascin from all mammalian species. 品种反应性 MouseHuman Species Reactivity Note Reactivity with other species has not been confirmed, but likely to react with all mammalian species. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002160.2
基因符号 - Cytotactin
- TNC
- Hexabrachion
- HXB
- GMEM
- TN
- Neuronectin
- Tenascin-C
- MGC167029
- JI
- TN-C
UniProt编号 - P24821
UniProt汇总 FUNCTION: SwissProt: P24821 # Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
SIZE: 2201 amino acids; 240866 Da
SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
PTM: N-glycosylated (By similarity).
SIMILARITY: SwissProt: P24821 ## Belongs to the tenascin family. & Contains 15 EGF-like domains. & Contains 1 fibrinogen C-terminal domain. & Contains 15 fibronectin type-III domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C for up to 12 months from date of receipt. Aliquot to avoid repeated freeze/thaw cycles. 包装信息 数量 50 µg
上一件merck millipore产品：merck millipore,默克密理博,MABF339,Anti-IL-4 (human) Antibody, PE, clone MP4-25D2
下一件merck millipore产品：merck millipore,默克密理博,MAB8991,Anti-LASP-1 Antibody, clone 8C6
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