merck millipore,默克密理愽
  • merck millipore,默克密理博,F1903,Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified

  • merck millipore,默克密理博,F1903,Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified

    产品名称：Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified
    产品型号：F1903


    merck millipore,默克密理博,F1903,Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified

  • 产品介绍
  • merck millipore,默克密理博,F1903,Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified

    重要规格表

    主要应用
    CULT
    描述
    产品目录编号 F1903
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified
    概述 Heparin-binding 40 kDa fragment of human plasma fibronectin purified from chymotryptic digest of human plasma fibronectin. This preparation contains the CS-1 heparin-binding region of fibronectin. Heparin-binding fragment promotes cytoskeleton organization in integrin signaling. This preparation shows one major band at 40 kDa in SDS-PAGE with no higher molecular weight species present. Smaller proteolytic fragments may be present.

    Human sourced raw material used in the production of this product tested negative for hepatitis B virus, hepatitis C virus (HCV), human immunodeficiency virus type-1 (HIV-1) and type-2 (HIV-2), human T-cell lymphotropic virus (HTLV-1 and HTLV-2) and Treponema pallidum. Handle as if potentially infectious.
    产品信息
    演示 Purified by gelatin-Sepharose™ and heparin-Sepharose™ column chromatography. Lyophilized from sodium citrate buffered saline, 20mM, NaCl 150mM, pH 7.4. Reconstitute with distilled water.
    应用
    主要应用
    • Cell Culture
    应用说明 ELISA

    Affinity chromatography

    Possibly for molecular mapping of fibronectin function

    Cell attachment and integrin signaling assays

    Optimal working dilutions must be determined by the end user.
    生物信息
    浓缩 1 mg/mL
    来源 Human
    品种 Human
    Entrez基因编号
    • NM_212482.1
    • NM_002026.2
    • NM_054034.2
    • NM_212474.1
    • NM_212475.1
    • NM_212476.1
    • NM_212478.1
    Entrez基因汇总 This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
    基因符号
    • FINC
    • FN1
    • DKFZp686O13149
    • DKFZp686H0342
    • DKFZp686I1370
    • MSF
    • FN
    • CIG
    • DKFZp686F10164
    • LETS
    UniProt编号
    • P02751
    UniProt汇总 FUNCTION: SwissProt: P02751 # Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Interaction with TNR mediates inhibition of cell adhesion and neurite outgrowth (By similarity).
    SIZE: 2386 amino acids; 262607 Da
    SUBUNIT: Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1.
    SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
    TISSUE SPECIFICITY: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.DEVELOPMENTAL STAGE: Ugl-Y1, Ugl-Y2 and Ugl-Y3 are present in the urine from 0 to 17 years of age.
    PTM: Sulfated.
    SIMILARITY: SwissProt: P02751 ## Contains 12 fibronectin type-I domains. & Contains 2 fibronectin type-II domains. & Contains 16 fibronectin type-III domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material at -20°C for up to one year from date of receipt. After reconstitution, maintain at -20°C for up to six months in undiluted aliquots. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 500 µg

    merck millipore,默克密理博,F1903,Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified

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下一件merck millipore产品：merck millipore,默克密理博,SF-907,miR-9-3p; Human, Cyanine 3, RNA Detection Probe,SmartFlare


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