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merck millipore,默克密理博,AB16311,Anti-Nitric Oxide Synthase II Antibody
产品名称:Anti-Nitric Oxide Synthase II Antibody
产品型号:AB16311
This Anti-Nitric Oxide Synthase II Antibody is validated for use in WB, IC for the detection of Nitric Oxide Synthase II.
merck millipore,默克密理博,AB16311,Anti-Nitric Oxide Synthase II Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB16311 Replaces AB1631 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Nitric Oxide Synthase II Antibody Alternate Names - iNOS
- NOS II
产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% Sodium azide as a preservative. 应用 应用 This Anti-Nitric Oxide Synthase II Antibody is validated for use in WB, IC for the detection of Nitric Oxide Synthase II. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Western Blot: 5 μg/mL using chemiluminescent detection. Higher concentrations of the antibody may be required if colorimetric detection is used. Antibody dilution will also vary with the concentration of the antigen. Immunocytochemistry: Use at 2-5 μg/mL
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to amino acids 1131-1144 of mouse macrophage NOS, coupled to KLH. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Reactive with mouse NOS-II (iNOS). 品种反应性 Mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000625.3
- NM_153292.1
Entrez基因汇总 Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. 基因符号 - EC 1.14.13.39
- NOS2A
- iNOS
- HEP-NOS
- INOS
- NOS
- NOS2
UniProt编号 - P35228
UniProt汇总 FUNCTION: SwissProt: P35228 # Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions.
COFACTOR: Heme group (By similarity). & Binds 1 FAD (By similarity). & Binds 1 FMN (By similarity). & Metrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme (By similarity).
SIZE: 1153 amino acids; 131117 Da
SUBUNIT: Homodimer. Binds SLC9A3R1.
TISSUE SPECIFICITY: Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
SIMILARITY: SwissProt: P35228 ## Belongs to the NOS family. & Contains 1 flavodoxin-like domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at 2-8°C in undiluted aliquots for up to 6 months. 包装信息 数量 100 µg
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