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merck millipore,默克密理博,AB1590P,Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168)
产品名称：Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168)
产品型号：AB1590P
Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168) is an antibody against Adenosine A3 Receptor for use in ELISA, IC & WB.
merck millipore,默克密理博,AB1590P,Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168)
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R WB, ELISA, ICC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB1590P 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168) 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA 应用 应用 Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168) is an antibody against Adenosine A3 Receptor for use in ELISA, IC & WB. 主要应用 - Western Blotting
- ELISA
- Immunocytochemistry
应用说明 Western blot: 1-10 micrograms per mL: A3 receptors are different sizes in different species & tissues; A3R from rat brain membranes runs as a 40kDa band, 52kDa in rabbit uroepithelium membranes (Yu, W et al. Am J. Physiol Cell Physiol 2006 in press); use proteinase inhibitors and membrane preparations for best signals.
ELISA: 1:10,000-1:50,000 (50-100 ng A3R peptide (Catalog Number AG294)/well)
Immunocytochemistry: Caufield, 2003. Light 2% PFA fixation 5-10 minutes --long fixations lower staining intensity.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Amino acid sequence corresponding to the 3rd extracellular domain (15 amino acids) of the rat A3R gene. 表位 extracellular (a.a. 154-168) 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Specific for Adenosine A3 receptor. Based on mRNA studies, the A3R has been found in rat testis and lung, kidneys, heart and brain. Other studies have found the mRNA to be highest in lung, spleen and pineal glands and moderate levels in brain kidney and testis. 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_020683.6
- NM_000677.3
- NM_001081976.1
Entrez基因汇总 This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. 基因符号 - ORFNames=UNQ1931/PRO4406
- ADORA3
- AD026
- RP11-552M11.7
- A3AR
- bA552M11.5
UniProt编号 - P33765
UniProt汇总 FUNCTION: SwissProt: P33765 # Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.
SIZE: 318 amino acids; 36185 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
PTM: Phosphorylation on Ser-317 may be crucial for rapid desensitization (By similarity).
SIMILARITY: SwissProt: P33765 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µg
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