merck millipore,默克密理愽
  • merck millipore,默克密理博,AB1580-I,Anti-Mu Opioid Receptor Antibody

  • merck millipore,默克密理博,AB1580-I,Anti-Mu Opioid Receptor Antibody

    产品名称：Anti-Mu Opioid Receptor Antibody
    产品型号：AB1580-I
    Detect Opioid Receptor using this rabbit polyclonal antibody, Anti-Mu Opioid Receptor Antibody validated for use in western blotting & IHC (Paraffin).

    merck millipore,默克密理博,AB1580-I,Anti-Mu Opioid Receptor Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB1580-I,Anti-Mu Opioid Receptor Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB1580-I
    Replaces AB1580
    描述 Anti-Mu Opioid Receptor Antibody
    Alternate Names
    • Anti-Opioid Receptor μ
    • Mu-type opioid receptor
    • M-OR-1
    • MOR-1
    • Mu opiate receptor
    • Mu opioid receptor
    • MOP
    • hMOP
    背景信息 Mu Opioid Receptor (MOP), also called Mu-type opioid receptor (MOR-1), is a receptor for natural and synthetic opioids such as beta-endorphin, endomorphin, morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. MOP functions as a class A G-protein coupled receptor (GPCR), but its down-regulation pathways vary with the agonist and may or may not be independent of G-protein coupling. Endogenous ligands induce rapid desensitization, endocytosis and recycling, as opposed to synthetic ligands, like morphine, that trigger only low desensitization and endocytosis. Hetero-oligomerization with other GPCRs can modulate agonist binding, signaling and trafficking properties. MOP is expressed in the brain and is involved in neurogenesis. MOP is the main physiological target for most clinically important opioid analgesics.
    产品信息
    格式 Affinity Purified
    控制
    • SH-SY5Y cell lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Opioid Receptor using this rabbit polyclonal antibody, Anti-Mu Opioid Receptor Antibody validated for use in western blotting & IHC (Paraffin).
    主要应用
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:1,000-4,000 dilution from a representative lot detected Mu Opioid Receptor in human cerebellum, mouse hippocampus, mouse midbrain, and rat midbrain tissue.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human Mu Opioid Receptor.
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes the C-terminus of Mu Opioid Receptor. This antibody will recognize isoform 1 (45 kDa), isform 10 (55 kDa), isoform 12 (34 kDa), and isoform 13 (36 kDa).
    品种反应性 MouseHuman
    Species Reactivity Note Demonstrated to react with Human and Mouse. Predicted to react with Rat, Porcine, and Bovine based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_000905
    基因符号
    • MOR1
    • OPRM1
    纯化方法 Affinity purified
    UniProt编号
    • P35372
    产品使用声明
    质量保证 Evaluated by Western Blotting in SH-SY5Y cell lysate.

    Western Blotting Analysis: 0.2 µg/mL of this antibody detected Mu Opioid Receptor in 10 µg of SH-SY5Y cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB1580-I,Anti-Mu Opioid Receptor Antibody

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