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品种反应性 主要应用 宿主 格式 抗体类型 R, M WB, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB1574 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-GABA Transporter-3 Antibody, CT Alternate Names - GAT-3
产品信息 格式 Affinity Purified 演示 Affinity purified antibody. Liquid in 0.1M PBS with 1% BSA and 0.1% sodium azide. 应用 应用 Detect GABA Transporter-3 using this Anti-GABA Transporter-3 Antibody, C-terminus validated for use in IH & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry: 1:500-1:750 on 4% paraformaldehyde fixed tissue.
It is recommended that the antibody is diluted in PBS containing 10% normal goat serum and 0.5% Triton X-100. AB1574 has been used for both light and electron microscopic studies of rat retina, cortex and hippocampus.
Western blot: It has been reported that this antibody works for Western blot (Minelli, 1996).
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 C-terminus of rat GAT-3 (aa 607-627) coupled to KLH (Johnson, 1996). This sequences is identical to amino acids 607-627 of mouse GAT-4 but shows no significant similarity to mouse GAT-3. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 GABA Transporter-3 (GAT-3), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected. 品种反应性 RatMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_014229.1
Entrez基因汇总 Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11.[supplied by OMIM] 基因符号 - GAT3
- SLC6A11
- GABT3
- GAT-3
UniProt编号 - P48066
UniProt汇总 FUNCTION: SwissProt: P48066 # Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
SIZE: 632 amino acids; 70606 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Widespread distribution in the brain.
SIMILARITY: SwissProt: P48066 ## Belongs to the sodium:neurotransmitter symporter (SNF) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 10 µg
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